Registration Dossier
Registration Dossier
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EC number: 700-677-9 | CAS number: 19190-61-5
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 011
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- methyl 2,2,3,3,4,4-hexafluoro-4-[(1,2,2-trifluoroethenyl)oxy]butanoate
- EC Number:
- 700-677-9
- Cas Number:
- 19190-61-5
- Molecular formula:
- C7H3F9O3
- IUPAC Name:
- methyl 2,2,3,3,4,4-hexafluoro-4-[(1,2,2-trifluoroethenyl)oxy]butanoate
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Details on test solutions:
- Stock solution with nominal concentration of 100 mg/l was stirred for 48 hours in a sealed vessel. Test solutions were prepared by dilution with medium.
Test organisms
- Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 72 h
Test conditions
- Test temperature:
- 21 - 24°C
- pH:
- 6,8 - 8,1
- Nominal and measured concentrations:
- The measured test substance concentration at the start and at the end of the exposure were below the detection limit. The measured concentrations of the hydrolyzed product at the start were 94-97% of the theoretical value and at the end of the exposure they were 89-98% of the theoretical value (assuming 100% hydrolysis).
- Reference substance (positive control):
- no
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- ca. 32 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- No adverse effect of the test substance and its hydrolyzed product were observed at a test concentration of 100 mg/l. The EC 50 value of the test substance is determined to be > 100 mg/l.
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