Registration Dossier
Registration Dossier
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EC number: 932-346-1 | CAS number: -
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Constituents approach and reference to annex IV of REACh.
- Adequacy of study:
- key study
- Study period:
- Not relevant
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- If all constituents of the substance are clearly known as readily biodegradable, the substance itself can be considered as readily biodegradable.
Moreover, the scientific knowledge about the constituents is very advanced, notably their metabolism in living organisms, from microorganisms to human.
Data source
Reference
- Reference Type:
- other: Statement based on Annex IV/V of REACh.
- Title:
- Readily biodegradability of Invert Sugar: Statement based on a constituents’ (Glucose, Fructose and Sucrose) approach.
- Author:
- RHDHV
- Year:
- 2 018
- Bibliographic source:
- RHDHV
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Constituents and substance are part of Annex IV/V of REACh.
Test material
- Reference substance name:
- (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal (3S,4R,5S)-1,3,4,5,6-pentahydroxyhexan-2-one hydrate
- EC Number:
- 932-346-1
- Cas Number:
- 8013-17-0
- Molecular formula:
- Not available due to the multiconstituent nature of the substance.
- IUPAC Name:
- (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal (3S,4R,5S)-1,3,4,5,6-pentahydroxyhexan-2-one hydrate
- Details on test material:
- - Name of test material (as cited in study report): invert sugar
Constituent 1
Study design
- Oxygen conditions:
- aerobic/anaerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- Any type of inoculum is able to use glucose, fructose and water as substrate.
Reference substance
- Reference substance:
- not required
Results and discussion
% Degradation
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Remarks:
- equivalent to
- Value:
- >= 100
- Remarks on result:
- other: Scientific knowledge on sugar metabolism.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Based on the extended scientific knowledge on the metabolism of the constituents glucose/fructose/and water, this substance is concluded as readily biodegradable.
- Executive summary:
Based on the extended scientific knowledge on the metabolism of the constituents glucose/fructose/and water, this substance is concluded as readily biodegradable.
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