Registration Dossier
Registration Dossier
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EC number: 931-250-7 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Justification for read across:
There are no specific experimental data available for MK-1 diesel fuel. Compositional and physico-chemical data show that MK-1 Diesel Fuel is very similar to Kerosine. It is considered appropriate, therefore, to read across from the Kerosine data to MK-1 Diesel Fuel. In that respect, the conclusions on the ecological toxicity endpoints for MK-1 Diesel Fuel will be the same for those of Kerosine. Further discussion on ecological toxicity will concern Kerosine, and data endpoints that are waived for Kerosine will be waived for MK-1 Diesel Fuel.
Short-term toxicity to aquatic invertebrates has been filled by read-across of measured data from kerosine. It is supported in a weight of evidence approach by a calculated value using composition information derived from two dimensional gas chromatography in conjunction with the PETROTOX model.
In a static read-across 48 -hour acute daphnid (Daphnia magna) test (OECD 202; KS=1), 20 animals/dose were exposed to Kerosine petroleum, hydrodesulfurised at nominal concentrations of 0, 0.1, 0.3, 1.4, 6.8, and 34 mg/L. The EL50 was 1.4 mg/L with a 95% confidence interval of 1.0 to 2.0 mg/L. The No Observed Effect Loading (NOEL) rate was 0.3 mg/L determined by immobilisation (Exxon, 1995d).
The toxicity for four kerosine products was tested using WAF methodology. In these reliable read-across supporting studies the 48 -hour EL50 (loading rate resulting in 50% immobilization of Daphnia) varied between 1.9 and 89 mg/L. The NOELs for these tests varied between 0.3 and 40 mg/L (Shell 1995, Shell 1994, Exxon 1995e, Exxon 1995f).
Results of computer modelling to estimate aquatic toxicity show no acute toxicity to freshwater invertebrates at or below its maximum attainable water solubility (Redman et al., 2010b).
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