Reaction mass of sodium chloride and sodium iodide and sodium sulphate

Short-term toxicity to fish

Administrative data

Endpoint:

short-term toxicity to fish

Type of information:

migrated information: read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

other information

Reliability:

2 (reliable with restrictions)

Data source

Reference

Reference Type:

publication

Title:

Chemical Substance Search (Sodium iodide)

Author:

Registered substances-ECHA

Bibliographic source:

http://echa.europa.eu/web/guest/information-on-chemicals/registered-substances?p_p_id=48_INSTANCE_Rfk8&_48_INSTANCE_Rfk8_iframe_q=Hydroquinone&_48_INSTANCE_Rfk8_iframe_legal=true

Materials and methods

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

Sodium iodide

EC Number:

231-679-3

EC Name:

Sodium iodide

Cas Number:

7681-82-5

Molecular formula:

INa

IUPAC Name:

Sodium iodide

Details on test material:

As sodium iodide is with 56% the main compound of this reaction mass a read-across of data from this salt to cover this endpoint for the reaction mass is assumed to be acceptable.

Sampling and analysis

Analytical monitoring:

yes

Test solutions

Vehicle:

yes

Test organisms

Test organisms (species):

other: Rainbow trout fry

Study design

Test type:

static

Water media type:

freshwater

Total exposure duration:

96 h

Test conditions

Details on test conditions:

The fish were fed a maintenance ration of a commercial pelleted trout food (Martin Feed Mills Limited, Ontario). The water supply for the continuous flow-through holding tanks was obtained from the Winnipeg River (in eastern Manitoba, Canada), purified by sand filtration and ultraviolet light sterilization, and distributed through polyvinylchloride pipes. Randomly selected fish were acclimated at I5°C (-2°C) for a period of >/5 days priorto testing. Feeding was suspended 24-h prior to and during the test period. The 96-h static tests were aerated and conducted at 15°C (±2°C) in a temperature- and photoperiod- (16-h light, 8-h dark) controlled facility. All fish holding and testing protocols followed the Ontario Ministry oft he Environment guidelines (Craig et al. 1983).

Results and discussion

Effect concentrations

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

4 500 mg/L

Nominal / measured:

meas. (not specified)

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

The acute toxicity of the substance to fish was conducted in a static test. After 96 hours of exposure a LC50 value of 4500 mg/L was obtained. No toxicity to fish was observed.

Executive summary:

The acute toxicity (96-h LC 50 ) of aqueous stable iodine species (I – , IO  3  –  , I 2 ) to rainbow trout and  Daphnia magna  were measured at three individual concentrations of hardness, total organic carbon, and chloride. Rainbow trout were most sensitive to I 2  (LC 50 0.53 mg/L), and much less sensitive to IO  3  –  (LC 50 220 mg/L) or I –  (LC 50 860 mg/L).  Daphnia magna  were equally sensitive to I 2  (LC 50 0.16 mg/L) and I –  (LC 50 0.17 mg/L), but were less sensitive to IO  3  –  (LC 50 10.3 mg/L). The external and internal radiological dose imparted by equivalent molar quantities of radioactive  125 I,  129 I, and  131 I were calculated for both the Daphnia  and trout using the LC 50  values obtained from a standard water treatment. As expected, the dose from  125 I and  131 I would exceed the expected lethal dose rate long before a chemically toxic level is reached. In contrast, a molar concentration of  129 I likely to cause death by chemical toxicity would impart a radiological dose less than that expected to be lethal. Thus, for short-lived aquatic organisms, risks due to chemical toxicity of  129 I may exceed risks due to its radioactive emissions.