Registration Dossier
Registration Dossier
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EC number: 909-701-4 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 48-hour EL50 (Daphnia magna) of reaction mass of cerium dioxide and lanthanum oxide and lanthanum fluoride is > 100 mg/L based on the mobility; revealing it is not harmful for the daphnids.
Key value for chemical safety assessment
Additional information
A GLP-compliant study, scored as Klimisch 1 and flagged as a key study, is available on the reaction mass; giving a 48h-EL50 > 100 mg/L and revealing that the reaction mass is not harmful to Daphnia magna (Bätscher, 2008).
Experimental studies, scored as Klimisch 2, are available on cerium dioxide (Bätscher, 2007) and lanthanum oxide (Seyfried, 2007) and also report no acute toxicity on daphnids. For cerium dioxide, this result is further support by bibliographical data of reliability 2 (Park et al., 2007) and 4 (Van Hoecke et al., 2007; Gaiser et al., 2007); giving the same conclusions. All these data on the two constituents were thus selecting as supporting studies.
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