Registration Dossier
Registration Dossier
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EC number: 908-381-3 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study performed to GLP and guideline
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 003
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- 10101-41-4
- EC Number:
- 600-148-1
- Cas Number:
- 10101-41-4
- IUPAC Name:
- 10101-41-4
- Reference substance name:
- calcium sulfate dihydrate
- IUPAC Name:
- calcium sulfate dihydrate
- Details on test material:
- - Name of test material (as cited in study report): Calcium sulfate dihydrate
- Analytical purity: 99.9%
- Lot/batch No.: Sigma Aldrich Corporation Lot. No. 109H0166
Constituent 1
Constituent 2
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Water flea
- Source: GSF Institute of Ecological Chemistry, Germany
- Age at study initiation: Juveniles (24 h old)
Study design
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 124 mg/L as Ca CO3
- Test temperature:
- 20.1 ± 0.2°C
- pH:
- 7.90 - 7.98
- Dissolved oxygen:
- 94 - 95%
- Nominal and measured concentrations:
- 100 mg/L (nominal)
- Details on test conditions:
- TEST SYSTEM
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 3
OTHER TEST CONDITIONS
- Adjustment of pH:
- Photoperiod: 16/8 (light/dark)
- Light intensity: 1221 - 1996 lux
- Reference substance (positive control):
- no
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 79 mg/L
- Nominal / measured:
- nominal
- Basis for effect:
- other: No mortalities observed
- Remarks on result:
- other: The LC50 for calcium sulfate dihydrate was > 100 mg/L. Results have been corrected for calcium sulfate anhydrous
- Details on results:
- No immobilisation or mortality were observed
Applicant's summary and conclusion
- Conclusions:
- The LC50 of calcium sulfate anhydrous to Daphnia magna is >79 mg/L.
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