2,3-difluoro-1-propoxy-4-[4-(trans-4-propylcyclohexyl)-1-cyclohexen-1-yl]-benzene

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

04.-07.07.2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

GLP compliance:

no

Type of method:

differential scanning calorimetry

Key result

Boiling pt.:

>= 403 - <= 405 °C

Atm. press.:

1 013 hPa

Decomposition:

no

Two DSC measurements in aluminium crucibles with a hole showed an endothermal effect after the melting in the temperature range below 164 °C. The onset temperature was derived from the intersection of the tangent line with the highest slope of the endothermal peak with the baseline. No further endothermic or exothermic effects were observed up to the final temperature (500 °C). The mass loss after the DSC measurements amounted to 100 %. Thus, the boiling point of the test item was determined to be in range from 403 to 405 °C.

Boiling point (DSC measurement

Ident No.	Test item / mg	Starting temperature/ °C	Final test temperature/ °C	Temperature range (endo- thelial) / °C	Onset (boiling) / °C	Crucible	Observations after the measurement
36351	7.34	25	500	390 - 450	403.4	Aluminium with a hole	Crucible empty
36355	7.64	25	500	385-450	404.5	Aluminium with a hole	Crucible empty

 

Conclusions:

The boiling point of the test item was determined to be in range from 403 to 405 °C.

Executive summary:

A study was conducted according to OECD test guideline 103, Regulation (EC) No 440/2008 method A.2 to determine the boiling point of the test item using differential scanning calorimetry. The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). Two tests with about 7 - 8 mg of the test item were performed. As reference crucible, an empty aluminium crucible was used. The test item and the reference were heated up from the starting temperature to the final temperature of 500 °C at a constant heating rate (10 K/min) in a defined atmosphere (nitrogen). Two DSC measurements in aluminium crucibles with a hole showed an endothermal effect after the melting in the temperature range below 164 °C. No further endothermic or exothermic effects were observed up to the final temperature (500 °C). The mass loss after the DSC measurements amounted to 100 %. Thus, the boiling point of the test item was determined to be in range from 403 to 405 °C.

Description of key information

The boiling point of the test item was determined to be in range from 403 to 405 °C (reference 4.3 -1).

Additional information

A study was conducted according to OECD test guideline 103, Regulation (EC) No 440/2008 method A.2 to determine the boiling point of the test item using differential scanning calorimetry. The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). Two tests with about 7 - 8 mg of the test item were performed. As reference crucible, an empty aluminium crucible was used. The test item and the reference were heated up from the starting temperature to the final temperature of 500 °C at a constant heating rate (10 K/min) in a defined atmosphere (nitrogen). Two DSC measurements in aluminium crucibles with a hole showed an endothermal effect after the melting in the temperature range below 164 °C. No further endothermic or exothermic effects were observed up to the final temperature (500 °C). The mass loss after the DSC measurements amounted to 100 %. Thus, the boiling point of the test item was determined to be in range from 403 to 405 °C.