Propanoic acid, 2,2-dimethyl-, 2-(1-amino-1-methylethyl)-4-[[[(4-fluorophenyl)methyl]amino]carbonyl]-1,6-dihydro-1-methyl-6-oxo-5-pyrimidinyl ester

Guidance on Safe Use

First-aid measures

Remove contaminated clothes. In case of unconsciousness move the person on his side to fresh air in a stable position. First aiders must take care first of all of their self-protection

Inhalation:

Move the affected person from the area and make it stretch, if breathing is difficult, give oxygen, if breathing is absent use mechanical ventilation. Consult a physician in symptoms appear..

Ingestion:

Do not induce vomiting unless on the advice of medical personnel, in case of vomiting tilt the patient forward or put it on the side with head facing down to keep the airways open and prevent aspiration.

Don’t give anything by mouth to people who give signs of drowsiness or numbness, or who are about to lose consciousness. Consult a physician in symptoms appear..

Skin contact:

Remove contaminated clothing and wash thoroughly with water. Consult a physician in symptoms appear.

Eyes contact:

Wash immediately with plenty of water for at least 15 minutes taking care to keep the eyelids separated the eye, contact lens should be removed only by experienced personnel. Consult a physician in symptoms appear

Fire-fighting measures

Extinguishing media: Water spray, foam, dry chemical, carbon dioxide.

Special hazards arising from the substance or mix.: When heated to decomposition or under fire conditions it could be emitted toxic fumes like carbon monoxide or other typical organic combustion products

Advice for firefighters Fire fighters should use self-contained breathing apparatus and protective clothing.

Accidental release measures

Report immediately the incident and remove of unnecessary personnel from the area. Stop the spread and isolate the spilled material; Isolate sewers discharging to superficial waters and/or segregate any water runoff into collection basins or tanks to facilitate processing or disposal. Do not release into the environment.

Clean Up Methods: Use a vacuum cleaner. If not possible, moisten dust with water before it is collected. Collect in containers and seal securely.  The personnel involved in containment and cleaning should wear appropriate personal protective equipment to minimize

exposure. The area must be thoroughly cleaned using adsorbent materials. Collected material should be placed in proper

container, labeled and sent to for final disposal.

Handling and storage

The substance should be handled in ventilated environment or with the appropriate local air extraction; minimize dust formation and avoid accumulation on surfaces; use antistatic equipment and clothing and prevent dust contact with possible ignition sources; avoid contact with eyes, skin and clothing. Remove contaminated clothes and wash thoroughly after handling.

Use container tightly closet and resistant, away from moisture and sunlight. Avoid contact with air and light. Properly label containers in case of pouring and clean external container surfaces with proper detergents and /or solvents.

Transport information

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Air transport (UN RTDG/ICAO/IATA)

Shipping

Special provisions / remarks

Remarks:

Not regulated for transportation.

SpecialProvisions

Exposure controls / personal protection

Respiratory Protection:

Use protective mask with P2 or P3 type dust filter (EN14387). If the substance is dissolved in organic solvent and manipulated in an open environment in significant quantities use an appropriate filter for chemicals (A type for boiling temperature > 65°C or Ax type for boiling temperature < 65°C) or ABEK type if simultaneous presence of others substances like, inorganic vapors, ammonia, etc

Protection for eyes / face:

Safety glasses goggles (EN 166), face shield or other full-face protection if it is required also airways protection.

Protection for skin / hands

Use chemical resistant gloves (EN374) with material compatible with solvent in which the substance is dissolved; the actual permeation time through te gloves and their life can be affected by mode of use, temperature and substance quantities handled

Technical controls and ventilation

Use general ventilation systems.Containment technologies suitable for controlling compounds are required to control at source and to prevent migration of the compound to uncontrolled areas -local exhaust ventilation and closed systems.

Laboratory: no general ventilation required for small quantities, low handling time and while using good laboratory practices. It’s always recommended to use fume cupboard or cabinet.; Can be provided

additional security according to specific “control band” established for the substance.

Stability and reactivity

Reactivity Information: No data available

Chemical stability: No data available

Possibility of hazardous reactions : No data available

Conditions to avoid Material is stable when kept in recommended normal storage conditions, No known chemical incompatibilities.

Disposal considerations

Avoid material contact with round or water (do not dispose in sewer systems). Waste materials should be stored in closed containers and disposed of preferably by incineration.

Containers should be sent to appropriate treatment and observe all local and national regulations for final disposal.