Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Concerning the acute oral toxicity of 2-(Trifluoromethyl)benzenesulfonamide two in vivo studies were performed. One can be assessed as reliable 
without restriction.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LD50
Quality of whole database:
2 acute oral in vivo studies are available with reliability Klimish 1 and 4.
Both studies comply with the OECD Principles of Good Laboratory Practice (GLP). The Klimish 1 study is used for classification and labelling
purposes.

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for selection of acute toxicity – oral endpoint
Guideline study 2003

Justification for classification or non-classification

According to the precautionary principle 2-(Trifluoromethyl)benzenesulfonamide a value of greater than 300 mg/kg and less than 2000 mg/kg body weight should be used for classification and labelling.