Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: No OECD method was following.

Data source

Reference
Reference Type:
other: calculation
Title:
Unnamed
Year:
2011

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Estimation by SciFinder using ACD/Labs software
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Tyrosine, N-(aminocarbonyl)-3-methoxy-O,α-dimethyl-
EC Number:
608-271-2
Cas Number:
28861-00-9
Molecular formula:
C13H18N2O5
IUPAC Name:
Tyrosine, N-(aminocarbonyl)-3-methoxy-O,α-dimethyl-

Results and discussion

Water solubility
Water solubility:
>= 0.51 - <= 999 g/L
Temp.:
25 °C
pH:
>= 1 - <= 10
Details on results:
Mass solubility :
at pH 1 (25 °C) = 0.51 g/l
at pH 2 (25 °C) = 0.56 g/l
at pH 3 (25 °C) = 1.0 g/l
at pH 4 (25 °C) = 5.9 g/l
at pH 5 (25 °C) = 54 g/l
at pH 6 (25 °C) = 460 g/l
at pH 7-10 (25 °C) = 999 g/l

Applicant's summary and conclusion

Conclusions:
At 25°C the test item is slightly soluble from pH 1 to 5, moderately soluble from pH 1 to 6 to 10.