Registration Dossier
Registration Dossier
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EC number: 617-219-8 | CAS number: 81334-34-1
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
The test substance is stable to hydrolysis at environmental relevant pH values and temperatures.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 325 d
- at the temperature of:
- 25 °C
Additional information
Key study (American Cyanamid Company, PD-M 19-8, 1982)
A hydrolysis study was conducted to determine the rate of hydrolysis and degradation products of the test substance at a concentration of 50 ppm in pH 5.0, 7.0 and 9.0 buffer solutions and in distilled water at 25 °C. The test substance was stable in aqueous buffer solutions (pH 5 and 7) and distilled water (pH 5.2) for up to 30 days at 25 °C. Only 1.0% of the test substance had degraded in each of the pH 5.0 and pH 7.0 buffer solutions, and 1.4% in the distilled water solution. The test item degraded slowly in an aqueous pH 9 buffer solution. At this pH 7, three % of the test item had degraded at the end of 30 days and the half-life at pH 9.0 was calculated to be 325 days. The only identified degradation product was Nicotinic acid, 2-[(1-carbamoyl-1,2-dimethylpropyl)-carbamoyl]-.
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