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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP-study according to OECD/EU guideline.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2001

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
2-chloro-3-isothiocyanatoprop-1-ene
EC Number:
604-275-3
Cas Number:
14214-31-4
Molecular formula:
C4H4ClNS
IUPAC Name:
2-chloro-3-isothiocyanatoprop-1-ene

Study design

Analytical monitoring:
yes

Results and discussion

Dissipation DT50 of parent compoundopen allclose all
pH:
9
Temp.:
50 °C
Hydrolysis rate constant:
1.05 h-1
DT50:
0.66 h
Type:
(pseudo-)first order (= half-life)
pH:
7
Temp.:
50 °C
Hydrolysis rate constant:
0.38 h-1
DT50:
1.81 h
Type:
(pseudo-)first order (= half-life)
pH:
4
Temp.:
50 °C
Hydrolysis rate constant:
0.29 h-1
DT50:
2.38 h
Type:
(pseudo-)first order (= half-life)
pH:
4
Temp.:
30 °C
Hydrolysis rate constant:
0.04 h-1
DT50:
15.37 h
Type:
(pseudo-)first order (= half-life)

Applicant's summary and conclusion

Conclusions:
The substance is hydrolytically not stable.