Registration Dossier
Registration Dossier
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EC number: 605-637-3 | CAS number: 172529-93-0
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 28.08.2007 - 30.10.2007
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
- Year:
- 2 007
- Report date:
- 2007
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: 92/69/EEC. A.6. Shake flask method.
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- flask method
Test material
- Reference substance name:
- 1,3-dimethyl 2-[2-(2-amino-6-chloro-9H-purin-9-yl)ethyl]propanedioate
- Cas Number:
- 172529-93-0
- Molecular formula:
- C12 H14 Cl N5 O4
- IUPAC Name:
- 1,3-dimethyl 2-[2-(2-amino-6-chloro-9H-purin-9-yl)ethyl]propanedioate
- Reference substance name:
- 2-Amino-6-chloro-9-(methyl-2-carbomethoxybutanoate-4- yl)purine
- IUPAC Name:
- 2-Amino-6-chloro-9-(methyl-2-carbomethoxybutanoate-4- yl)purine
- Details on test material:
- Formula: C12H14ClN5O4
Appearance: White to pale yellow solid
Expiry Date: 31 December 2007
Constituent 1
Constituent 2
Results and discussion
Water solubilityopen allclose all
- Water solubility:
- 146 mg/L
- Temp.:
- 10 °C
- pH:
- ca. 7.8
- Water solubility:
- 232.3 mg/L
- Temp.:
- 20 °C
- pH:
- 7.2
- Water solubility:
- 395.2 mg/L
- Temp.:
- 30 °C
- pH:
- 6.8
Any other information on results incl. tables
The preliminary water solubility of "Fam-stage-1" is 262 mg/L at 20 °C. The result of the estimation of the water solubility is of limited reliability and only serves to choose the method for the main test (higher or lower than 10 mg/L, according to the guidelines).
Mean: 146.0 mg/L, standard deviation: 7.7, three replicates, temperature 10.0 °C.
Mean: 232.3 mg/L, standard deviation: 8.3, three replicates, temperature 20.0 °C.
Mean: 395.2 mg/L, standard deviation: 5.2, three replicates, temperature 30.0 °C.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
