Registration Dossier
Registration Dossier
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EC number: 432-770-2 | CAS number: 139189-30-3
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
The 28-Day EC50(reduction in emergence) and 28 EC50 (reproduction) measured in sediment-dwelling larvae of Chironomus riparius and sediment-dwelling oligochaete, Lumbriculus variegatus. The 28-Day EC50(reduction in emergence) and 28 EC50 (reproduction) based on nominal test concentrations was greater than 1000 mg/kg. The No Observed Effect Concentration was equal to or greater than 1000 mg/kg.
Key value for chemical safety assessment
- EC50 or LC50 for freshwater sediment:
- 1 000 mg/kg sediment dw
- EC10, LC10 or NOEC for freshwater sediment:
- 1 000 mg/kg sediment dw
Additional information
Data from two studies are available to assess the toxicity of the test item to the sediment-dwelling larvae of Chironomus riparius and sediment-dwelling oligochaete, Lumbriculus variegatus.
The methods followed recommendations of the OECD Guidelines for Testing of Chemicals No. 218 (April 2004) "Sediment-Water Chironomid Toxicity Test using Spiked Sediment" and method of the OECD Guidelines for the Testing of Chemicals (2004), "Sediment-water LumbriculusToxicity Test using Spiked Sediment", OECD Guideline No. 225, October 2007 respectively. All data were gatheredin accordance with the Principles of Good Laboratory Practice (GLP) and reported with a valid GLP certificate.
Both studies were conducted over a 28-day exposure period at a nominal equivalent to 1000 mg/l. All measured concentrations were shown to be ≥90% of starting concentrations.
The 28-Day EC50(reduction in emergence) and 28 EC50 (reproduction) based on nominal test concentrations was greater than 1000 mg/kg. The No Observed Effect Concentration was equal to or greater than 1000 mg/kg.
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