Registration Dossier
Registration Dossier
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reaction mass of: tetrasodium 7-(4-(4-fluoro-6-(4-(2-sulfonatoethylsulfonyl)phenylamino)-1,3,5-triazin-2-ylamino)-2-ureidophenylazo)naphthalene-1,3,6-trisulfonate;tetrasodium 7-(4-(4-hydroxy-6-(4-(2-sulfonatoethylsulfonyl)phenylamino)-1,3,5-triazin-2-ylamino)-2-ureidophenylazo)naphthalene-1,3,6-trisulfonate
EC number: 427-650-1 | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 March 1998 to 24 April 1998
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- yes
- Remarks:
- The study has to be performed with amounts 5 times higher than the water solubility determined by preliminary experiments) (refer amendment no.1, dated April 29, 1998).
- Principles of method if other than guideline:
- The solution obtained from dissolving the test substance in water showed a high viscosity. Therefore it was decided to perform the experiments with amounts lower than required by the guideline (Requirement of the guideline: The study has to be performed with amounts 5 times higher than the water solubility determined by preliminary experiments) (refer amendment no.1, dated April 29, 1998).
- GLP compliance:
- yes
- Type of method:
- flask method
- Key result
- Water solubility:
- 636.2 g/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 5.6
- Conclusions:
- Water solubility of the test substance at a temperature of 20°C: 636.2 g/L (RSD:7%) based on test material
- Executive summary:
Study conducted to EU test guidance 92/69/EEC part A6 using the HPLC analysis method in compliance with GLP.
Water solubility of the test substance at a temperature of 20°C: 636.2 g/L (RSD:7%) based on test material. The substance is considered to be very soluble in water.
Reference
Description of key information
Water solubility of the test substance at a temperature of 20°C: 636.2 g/L (RSD:7%) based on test material
Key value for chemical safety assessment
- Water solubility:
- 636.2 g/L
- at the temperature of:
- 20 °C
Additional information
Study conducted to EU test guidance 92/69/EEC part A6 using the HPLC analysis method in compliance with GLP.
Water solubility of the test substance at a temperature of 20°C: 636.2 g/L (RSD:7%) based on test material. The substance is considered to be very soluble in water.
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