Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 307-593-8 | CAS number: 97675-24-6
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
postive reactions in 15% of test animals is required for a positive senisitising result in a non-adjuvant test. Fewer than prescibed test animals were utilised, therfore decreasing the power of the study to detect a sensitiser. 40-50% of animals displayed a positive result on first challenge, 10-20% of animals displayed a positive reaction on rechallenge, with a lower concentration of test material, and 40% of animals displayed reactions on second rechallenge, with a lower concentration of test substance. therefore, according to guidelines, this substance is a sensitser.
Migrated from Short description of key information:
In a dermal sensitization study with sodium 4-icosylbenzenesulfonatein mineral oil, guinea pigs (5/sex) were tested with a Beuhler test.
In this study,sodium 4-icosylbenzenesulfonateis a dermal sensitizer.
Justification for selection of skin sensitisation endpoint:
postive reactions in 15% of test animals is required for a positive senisitising result in a non-adjuvant test. Fewer than prescibed test animals were utilised, therfore decreasing the power of the study to detect a sensitiser. 40-50% of animals displayed a positive result on first challenge, 10-20% of animals displayed a positive reaction on rechallenge, with a lower concentration of test material, and 40% of animals displayed reactions on second rechallenge, with a lower concentration of test substance. therefore, according to guidelines, this substance is a sensitser.
Respiratory sensitisation
Endpoint conclusion
- Additional information:
No aplicable
Justification for classification or non-classification
Adverse effect observed
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
