Fatty acids, rape-oil, hydrogenated, reaction products with diethylenetriamine, di-Me sulfate-quaternized

Adsorption / desorption

Link to relevant study record(s)

Reference

Endpoint:

adsorption / desorption: screening

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From September 20, 2010 to September 21, 2010

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))

Deviations:

no

GLP compliance:

yes

Type of method:

HPLC estimation method

Media:

soil/sewage sludge

Radiolabelling:

no

Test temperature:

ca. 30°C

Details on study design: HPLC method:

- HPLC system equipped with ultraviolet and charged aerosol detectors (HPLC/UV/CAD)
Instrument: Alliance Separation Module 2695 (Waters, Milford, MA, USA), Detector: Dual λ Absorbance Detector 2487 (Waters) and CAD Series ESA CAD Plus, Column: Agilent Zorbax, 250 mm x 4.6 mm i.d., dp = 5 μm (Thermo Fisher Scientific, Waltham, MA, USA), Column temperature: 30.0°C +/- 2.5°C, Mobile phase: ammonium bicarbonateand acetonitrile, Flow: 1.0 mL/min, Injection volume: 10 μL, UV detection: 220 nm.
Analysis of the retention time
- Duplicate injections for each conditions

Key result

Type:

Koc

Remarks:

for sewage sludge

Value:

< 33.1 L/kg

Temp.:

30 °C

Remarks on result:

other: log Koc = < 1.52

Remarks:

pH: not specified

Key result

Type:

Koc

Remarks:

for soil

Value:

< 18.2 L/kg

Temp.:

30 °C

Remarks on result:

other: log Koc = < 1.26

Remarks:

pH: not specified

Details on results (HPLC method):

The retention factor was recorded and the log Koc was then determined from linear regression.

Validity criteria fulfilled:

yes

Conclusions:

Under the study conditions, the mean adsorption coefficient (Koc) of the test substance was determined to be <33.1 (mean log Koc = < 1.52) for sewage sludge and < 18.2 (mean log Koc = < 1.26) for soil.

Executive summary:

A study was conducted to determine the adsorption coefficient of the test substance, 'di-C18-22 AAEMIM-MS' (active: 100%), according to OECD Guideline 121, in compliance with GLP. An HPLC system equipped with ultraviolet and charged aerosol detectors (HPLC/UV/CAD) was used to determine the Koc and log Koc of the test substance in a soil/sewage sludge media at ca. 30°C. The retention factor was recorded and the log Koc was then determined from linear regression for the test and reference substances. The test substance was not retained on the chromatographic system. Under the study conditions, the mean adsorption coefficient (Koc) of the test substance was determined to be <33.1 (mean log Koc = < 1.52) for sewage sludge and < 18.2 (mean log Koc = < 1.26) for soil (Springborn, 2010).

Description of key information

Based on the results of the study, adsorption coefficient of the test substance, ‘di-C18-22 AAEMIM-MS’ was determined to be <33.1 (mean log Koc = < 1.52) for sewage sludge and < 18.2 (mean log Koc = < 1.26) for soil at 20°C. Using these Koc values and respective weight fraction organic carbon suspended solids, sediment solids and soil from R.16 ECHA Guidance (i.e., FOCsusp of 0.1, FOCsediment of 0.05 and FOCsoil of 0.02), the distribution coefficient for adsorption in suspended matter (surrogate for sewage sludge; Kpsusp), sediment (Kpsediment) and soil (Kpsoil) values of 0.52, 0.22 and -0.44 have been taken forward for risk assessment respectively.

Key value for chemical safety assessment

Koc at 20 °C:

33.1

Other adsorption coefficients

Type:

log Kp (solids-water in activated sewage sludge)

Value in L/kg:

0.52

at the temperature of:

20 °C

Other adsorption coefficients

Type:

log Kp (solids-water in sediment)

Value in L/kg:

0.22

at the temperature of:

20 °C

Other adsorption coefficients

Type:

log Kp (solids-water in soil)

Value in L/kg:

-0.44

at the temperature of:

20 °C

Additional information

A study was conducted to determine the adsorption coefficient of the test substance, 'di-C18-22 AAEMIM-MS' (active: 100%), according to OECD Guideline 121, in compliance with GLP. An HPLC system equipped with ultraviolet and charged aerosol detectors (HPLC/UV/CAD) was used to determine the Koc and log Koc of the test substance in a soil/sewage sludge media at ca. 30°C. The retention factor was recorded and the log Koc was then determined from linear regression for the test and reference substances. The test substance was not retained on the chromatographic system. Under the study conditions, the mean adsorption coefficient (Koc) of the test substance was determined to be <33.1 (mean log Koc = < 1.52) for sewage sludge and < 18.2 (mean log Koc = < 1.26) for soil (Springborn, 2010). Using these Koc values and respective weight fraction organic carbon sediment solids and soil from R.16 ECHA Guidance (i.e., FOCsusp of 0.1 and FOCsoil of 0.02), the distribution coefficient for adsorption in in suspended matter (surrogate for sewage sludge; Kpsusp) and soil (Kpsoil) values of 0.52 and -0.44 have been taken forward for risk assessment of sewage sludge and soil respectively.