α-Bitter acids, hop, hydrogenated, isomerized

Water solubility

Administrative data

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Justification for type of information:

Water solubility measured as part of EC Physico/Chemical Test A5, Surface Tension (Ring Method).

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2017

Report date:

2017

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: EU Regulation (EC) 440/2008, Annex Part A test A5 and OECD Test Guideline 115

GLP compliance:

yes

Type of method:

other: EU Regulation (EC) 440/2008, Annex Part A test A5 and OECD Test Guideline 115

Test material

Test material information

Constituent 1

Reference substance name:

Not assigned. This is a fraction of a hop extract (CAS 8060-28-4)

IUPAC Name:

Not assigned. This is a fraction of a hop extract (CAS 8060-28-4)

Test material form:

solid

Remarks:

Resinous solid. Becomes flowable above 60 oC.

Specific details on test material used for the study:

Batch no. EXP 5

Results and discussion

Water solubility

Key result

Water solubility:

< 1 mg/L

Conc. based on:

test mat.

Incubation duration:

ca. 2 h

Temp.:

20 °C

pH:

ca. 7

Details on results:

A solution of 1g/L was made up, the test sample floated at the top of the solution. It was then sonicated for 2 hours and the solution turned a pale yellow with some of the sample still floating at the top of the solution. A second solution of 1mg/L was made up; the sample remained floating on the surface of the solution. Therefore testing does not need to be conducted.

Applicant's summary and conclusion

Conclusions:

Testing for surface tension revealed that the solubility of hop extract, beta acids, potassium salt in water is less than 1 mg per litre. This is entirely as expected - the UVCB substance contains hydrophobic substances.