Registration Dossier
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EC number: 274-503-0 | CAS number: 70247-74-4
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 March 2015 - 20 March 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Specific details on test material used for the study:
- Lot. AT-0032668200
- Water solubility:
- 31.8 mg/L
- Conc. based on:
- test mat. (total fraction)
- Incubation duration:
- 72 h
- Temp.:
- 20 °C
- Remarks on result:
- other: pH is not known
- Details on results:
- The preliminary visual experiments showed that the water solubility of the test item is about 40 mg/l.
- Conclusions:
- The water solubility (cs) of FAT 20035/E at a temperature of 20 °C was determined to 31.8 mg/l.
- Executive summary:
The purpose of the study was determination of the water solubility cs of the test item according to the European Commission Regulation (EC) No.440/2008 Part A: methods of determination of physico –chemical properties.A6. Water solubility , flask – method and OECD test guidelines OECD 105 water solubility.
The preliminary visual experiments showed that the water solubility of the test item is about 40 mg/l. So, based on the study results the water solubility (cs) of FAT 20035/E at a temperature of 20 °C was determined to 31.8 mg/l.
Reference
Table: Water solubility of the test item – experiments A to D
Experiment | A | B | C | D(blank) |
Amount of test item(mg) | 1000 | 1000 | 1000 | --- |
Stirring time at 30 °C (h) | 24 | 48 | 72 | 72 |
Measured concentration (μg/ml) | 3,28 | 3.11 | 3.15 | --- |
Aliquot | 1.0/10 ml | 1.0/10 ml | 1.0/10 ml | 1.0/10 ml |
Water solubility (mg/l) | 32.8 | 31.1 | 31.5 | --- |
Average experiments A to C: 31.8 mg/l.
Description of key information
The water solubility (cs) of test substance at a temperature of 20 °C was determined to 31.8 mg/l.Key value for chemical safety assessment
- Water solubility:
- 31.8 mg/L
- at the temperature of:
- 20 °C
Additional information
The purpose of the study was determination of the water solubility cs of the test item according EU method A6 and OECD test guidelines OECD 105. The preliminary visual experiments showed that the water solubility of the test item is about 40 mg/l. So, based on the study results the water solubility (cs) of FAT 20035/E at a temperature of 20 °C was determined to 31.8 mg/l.
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