Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 274-324-8 | CAS number: 70131-50-9
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
In the key study (Bradshaw 2010) skin sensitisation was assessed using the local lymph node assay. Three groups of four mice were treated with 50 µL of the test material at concentrations of 10%, 5% or 2.5% w/w in dimethyl sulphoxide. A further group of four animals were treated with dimethyl sulphoxide alone. The test material was considered to be a non-sensitiser under the conditions of the test.
Migrated from Short description of key information:
Skin sensitisation study (OECD 429). Bentonite is not a skin sensitizer in accordance with the local lymph node assay.
Justification for classification or non-classification
Bentonite acid leached was not considered to be a skin sensitiser in the LLNA and therefore does not warrant classifcation in accordance with CLP.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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