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EC number: 272-727-3 | CAS number: 68909-99-9
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The test substance not readily biodegradable (according to OECD criteria), but moderately biodegradable.
Key value for chemical safety assessment
Additional information
Data on the biodegradability of the mixture N3/N4-amine are not available. Therefore, the assessment is based on the available experimental data for the constituents N-(2 -aminoethyl)-1,3 -propanediamine (CAS 13531-52-7), N,N'-bis(3 -aminopropyl)ethylenediamine (CAS 10563-26-5) and ethylenediamine (CAS 107-15-3), as well as for the structurally similar substance trientine (CAS 112-24-3). In addition, the biodegradation potential was estimated for the constituent N1,N1'-(iminodi-2,1-ethanediyl)bis -1,3-propanediamine (CAS 112-24-3). The data are listed in the table below:
RA- Substance |
Fraction |
Guideline / Model; Reference |
Inoculum |
Biodegradation after 28 d |
Conclusion |
Experimental data |
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CAS 13531-52-7 |
> 25 - < 35% |
Similar to OECD 301F (BASF AG, 1991) |
domestic activated sludge, (adaptation not specified) |
50 – 60% (O2-consumption) |
not readily biodegradable (according to OECD criteria), but biodegradable |
Similar to OECD 301F (BASF AG, 1991) |
domestic activated sludge, adapted |
55% (O2-consumption) |
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CAS 107-15-3 |
> 5 - < 15% |
OECD 301C (JETOC, 1991) |
mixture of sewage, soil and natural water |
94 – 96% (O2-consumption) |
readily biodegradable (according to OECD criteria) |
CAS 10563-26-5 |
> 45 - < 55% |
OECD 301B (BMG AG, 2012) |
activated sludge, domestic, non-adapted |
70% (CO2-evolution) |
readily biodegradable (according to OECD criteria) |
CAS 112-24-3 |
None (structural analogue) |
OECD 301D (SIDS; Bayer AG, 1998) |
domestic activated sludge, adapted |
0% (parameter unspecified) |
not readily biodegradable (according to OECD criteria) |
Calculated data |
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CAS 58214-71-4 |
≥ 0 - < 8% |
OASIS Catalogic v5.11.17, CATALOGIC Kinetic 301B v.02.09 (BASF SE, 2016) |
- |
19% (CO2-evolution; in AD*) |
not readily biodegradable (according to OECD criteria), but moderately biodegradable |
OASIS Catalogic v5.11.17, CATALOGIC 301C v08.12 (BASF SE, 2016) |
- |
18% (CO2-evolution; in AD) |
|||
OASIS Catalogic v5.11.17, CATALOGIC Kinetic 301F v13.16 (BASF SE, 2016) |
- |
27% (BOD; in AD) |
|||
EPI Suite v4.11, BIOWIN v4.10 |
- |
Prediction: readily biodegradable. (not in domain) |
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*AD: applicability domain
Overall conlusion:
Based on a weight-of-evidence approach by the available data for the constituents of N3/N4 –amine and an additional structurally analogous compound, the mixture is concluded to be not readily biodegradable (according to OECD criteria), but moderately biodegradable.
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