Registration Dossier
Registration Dossier
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EC number: 252-471-9 | CAS number: 35265-04-4
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
2-[(1-methylpropyl)amino]ethanol was considered hydrolytically stable.
Key value for chemical safety assessment
Additional information
The hydrolysis as a function of pH of 2-[(1-methylpropyl)amino]ethanol was determined in a test performed according to OECD 111 and GLP requirements (Xiaoqian, 2011). During the preliminary test performed at 50°C for 5 days, the substance has been found to be hydrolytically stable at all the tested pH. Indeed, the results showed that the hydrolysis percentages of samples were 0.35%, 9.08% and 5.23% respectively in buffers solution of pH 4.0, 7.0 and 9.0. Since less than 10% of the reaction was observed after 5 days, 2-[(1-methylpropyl)amino]ethanol was considered hydrolytically stable. Therefore, no advanced test was required.
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