Registration Dossier
Registration Dossier
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EC number: 237-523-0 | CAS number: 13825-74-6
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
In accordance with Column 2 of REACH Annex VII, the skin sensitisation study does not need to be conducted as the substance is corrosive. Due to the sulphuric acid related corrosivenes of target compound titanium oxide sulphate, no valid data for the classification of skin sensitising potential are available. No reports on skin sensitisation of humans after occupational exposure are available. Moreover, titanium dioxide, which would be the finally resulting stable compound after completion of the hydrolysis reaction, clearly is not a sensitizer. Based on these consideration, target chemical titanium oxide sulphate is being assessed as not sensitising.
Migrated from Short description of key information:
The sensitisation potential of titanium oxide sulphate is not accessible due to release of sulphuric acid when in contact with wet material.
Justification for classification or non-classification
The sensitising potential of titanium oxide sulphate is not accessible due to sulphuric acid related corrosivity when in contact with wet material. Neither target substance titanium oxide sulphate, nor final hydrolysis product titanium dioxide are considered to be sensitizers, thus no classification according to CLP/GHS or DSD.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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