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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
0.1 mg/L

Additional information

There are ten short-term fish toxicity studies, with all of the studies being based on read across data. The key study is a 48 hour acute study in fathead minnow, Pimephales promelas eggs. The eggs were exposed to hydrazine at nominal concentrations ranging from 0-5 mg/l. The LOEC was reported to be 0.1 mg/l with the effects being observed in hatching, growth rates, physiological anomalies, development and deformities. The study is classified as Klimisch Code 2 (reliable with restriction) as it was well reported and detailed and in a peer review publication.

The supporting studies include the following data a 96-hour NOEC of 0.43 mg/l in the bluegill,Lepomis macrochirus; a 48-hour LC50 of 0.75 mg/l in the golden orfe,Leucius idus melanotus; a 96-hour LC50 of 1 mg/l in the channel catfish,Ictalurus punctatus; two 96-hour LC50s of 1.08 mg/l in the bluegill,Lepomis macrochirus; 96-hour LC50s of 1.6, 1.0 and 1.2 mg/l in the bluegill,Lepomis macrochirus; a 96-hour LC50 of 1.12 mg/l in the golden shiner,Notemigonus crysoleucas; and 96-hour LC50s of 3.85 and 0.61 mg/l in the common guppy,Lebistes reticulatesand a 96-hour LC50 of 5.98 mg/l in fathead minnows.