Registration Dossier
Registration Dossier
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EC number: 233-713-2 | CAS number: 10326-41-7
Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to bees: acute contact
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
- Reason / purpose for cross-reference:
- read-across source
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LD50
- Effect conc.:
- > 100.4 µg per animal
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Validity criteria fulfilled:
- yes
- Conclusions:
- The contact LD50 value of SY-83 (L-(+)-lactic acid) in the honey bee was determined to be greater than 100.4 µg/bee, the highest concentration tested.
- Executive summary:
Mortality rates in all five treatment groups were similar to those observed in the control and solvent control groups. Mortalities did not appear to be treatment related. In conclusion, SY-83 was classified as relatively non-toxic to honey bees. The 48 hour contact LD50 value for SY-83 to honey bees was greater than 100.4 µg/bee, the highest dosage tested.
This information is used in a read-across approach in the assessment of the target substance. For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
Reference
Description of key information
The contact LD50 value of lactic acid in the honey bee was determined to be greater than 100.4 µg/bee, the highest concentration tested.
Key value for chemical safety assessment
Additional information
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