Registration Dossier
Registration Dossier
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EC number: 232-089-9 | CAS number: 7785-87-7
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study conducted to basic scientific principles, although only useful as supporting information as the result is an outlier compared to the weight of evidence from other results.
Data source
Reference
- Reference Type:
- publication
- Title:
- Acute toxicity of manganese to brown trout (salmo trutta) in hard water
- Author:
- Davies H & Brinkman S
- Year:
- 1 995
- Bibliographic source:
- Federal aid Project #F-243, Colorado Division of Wildlife, Fort Collins, Colorado
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- A flow-through toxicity test using a modified Mount and Brungs diluter which delivered two liters of each concentration per cycle to 92 litre aquaria.Median lethal concentration (LC50) was detemlined using probit (Finney 1971) and Spearman-Karber (Hamilton et al. 1977 and 1978) methods
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Manganese sulphate
- EC Number:
- 232-089-9
- EC Name:
- Manganese sulphate
- Cas Number:
- 7785-87-7
- Molecular formula:
- H2O4S.Mn
- IUPAC Name:
- manganese(2+) sulfate
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test organisms
- Test organisms (species):
- Salmo trutta
Study design
- Test type:
- flow-through
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 49.9 mg/L
- Conc. based on:
- other: Mn
- Basis for effect:
- mortality (fish)
Any other information on results incl. tables
- Sublethal observations / clinical signs:
Manganese concentrations were close to nominal values and were constant throughout the experiment. The LC50 in hard water (49.9mg Mn/L) is considerably higher than that for brown trout in much softer water (3.8 mg Mn/l) (Davies and Brinkrnan 1994). Therefore the difference between LC50s is due primarily to differences in water quality characteristics.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The LC50 was 49.9 mg Mn/L.
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