Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 228-507-4 | CAS number: 6284-43-1
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Effect on fertility: via oral route
- Endpoint conclusion:
- no adverse effect observed
Effect on fertility: via inhalation route
- Endpoint conclusion:
- no study available
Effect on fertility: via dermal route
- Endpoint conclusion:
- no study available
Additional information
All available studies on toxicity to reproduction of Glycerides resulted in NOAELs ≥ 1000 mg/kg bw/day:
Reproductive/developmental toxicity screening studies (OECD 422): NOAEL (male/female) ≥ 1000 mg/kg bw/day
Two-generation reproduction toxicity and developmental neurotoxicity study (OECD 416/426): NOAEL (P; male/female) ≥ 1159/2200 mg/kg bw/day NOAEL (F1; male/female) ≥ 1342/2262 mg/kg bw/day
Effects on developmental toxicity
Description of key information
All available studies on developmental toxicity and teratogenicity of Glycerides resulted in NOAELs ≥ 1000 mg/kg bw/day:
Rat: NOAEL (F1/F2 ≥ 1342/2262 mg/kg bw/day (OECD 416/426)
Rabbit: NOAEL = 1000 mg/kg bw/day (similar to OECD 414)
Mouse: NOAEL = 9540 mg/kg bw/day (teratogenicity study)
Effect on developmental toxicity: via oral route
- Endpoint conclusion:
- no adverse effect observed
Effect on developmental toxicity: via inhalation route
- Endpoint conclusion:
- no study available
Effect on developmental toxicity: via dermal route
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
