Registration Dossier
Registration Dossier
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EC number: 226-551-9 | CAS number: 5423-22-3
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
In a 72-h toxicity study conducted according to OECD guideline 201, microalgae (Pseudokirchneriella subcapitata) were exposed to Guanidine phosphate (1:1). The 72-h EC50 for growth rate reduction was 110 mg/L (corresponding to 36 mg guanidine/L) and the 72h-NOEC for growth rate reduction was 10 mg/L (corresponding to 3.3 mg guanidine/L) based on analytically confirmed nominal concentrations. The study is considered to be reliable without restrictions.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 110 mg/L
- EC10 or NOEC for freshwater algae:
- 10 mg/L
Additional information
In a 72-h toxicity study conducted according to OECD guideline 201, microalgae (Pseudokirchneriella subcapitata) were exposed to Guanidine phosphate (1:1) under static conditions at the following nominal concentrations (final test): 0 (blank control), 10, 22, 46, 100 and 220 mg/L. The test substance significantly reduced growth rate at 22 mg/L and higher. The 72-h EC50 for growth rate reduction was 110 mg/L (corresponding to 36 mg guanidine/L) and the 72h-NOEC for growth rate reduction was 10 mg/L (corresponding to 3.3 mg guanidine/L) based on analytically confirmed nominal concentrations. The study is considered to be reliable without restrictions.
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