Trimetazidine

Guidance on Safe Use

First-aid measures

Inhalation :

Move affected person to fresh air. Keep person warm and at rest. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. Get medical advice/attention. If unconscious, place in recovery position and get medical attention immediately.

Ingestion :

Wash out mouth with water. Keep person warm and at rest. Get medical attention immediately.

Skin contact :

Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Get medical attention immediately.

Eye contact : Get medical attention immediately. Immediately flush eyes with plenty of water, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Continue to rinse for at least 10 minutes.

Protection of first-aiders : Put on appropriate personal protective equipment (see Section 8). No action shall be taken involving any personal risk or without suitable training.

Fire-fighting measures

Extinguishing media :

Suitable extinguishing media : Use dry chemical or CO2

Unsuitable extinguishing media : None known

Special hazards arising from the substance or mixture :

Hazards from the substance or mixture : Flammable liquid and vapour. In a fire or if heated, a pressure increase will occur and the container may burst. Runoff to sewer may create fire or explosion hazard.

Fire water contaminated with this material must be contained and prevented from being discharged to any waterway, sewer or drain.

Hazardous combustion products : Decomposition products may include the following materials:

carbon dioxide

carbon monoxide

nitrogen oxides

Advice for firefighters :

Special precautions for fire-fighters:

Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. Move containers from fire area if this can be done without risk. Use water spray to keep fire-exposed containers cool.

Special protective equipment for fire-fighters:

Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Accidental release measures

Personal precautions, protective equipment and emergency procedures:

Protection of fire-fighters: Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilt material. Shut off all ignition sources. Do not breathe vapour or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment.

Environmental precautions:

Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). May be harmful to the environment if released in large quantities.

Methods and materials for containment and cleaning up Spill :

Stop leak if without risk. Prevent entry into sewers, water courses, basements or confined areas. Contain and collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or diatomaceous earth and place in container for disposal according to local regulations. Use spark-proof tools and explosionproof equipment.

Handling and storage

Precautions for safe handling:

Protective measures:

Put on appropriate personal protective equipment (see Section 8). Use spark-proof tools and explosion-proof equipment. Take precautionary measures against electrostatic discharges. Do not get in eyes or on skin or clothing. Do not breathe vapour or mist. Avoid release to the environment. Use only with adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Store and use away from heat, sparks, open flame or any other ignition source. Keep away from acids.

Advice on general occupational hygiene : Remove contaminated clothing and protective equipment before entering eating areas. Workers should wash hands and face before eating, drinking and smoking.

Conditions for safe storage, including any incompatibilities:

Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see Section 10) and food and drink. Eliminate all ignition sources. Separate from acids. Separate from oxidizing materials. Use appropriate containment to avoid environmental contamination. Keep container tightly closed and sealed until ready for use.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

2734

Shipping

Special provisions / remarks

Special provisions:

Transport within user’s premises:
always transport in closed containers that are upright and secure. Ensure that persons transporting the product know what to do in the event of an accident or spillage.

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Air transport (UN RTDG/ICAO/IATA)

UN number:

2734

Shipping information

Proper shipping name and description:

Not available.

Special provisions / remarks

Remarks:

Transport within user’s premises:
always transport in closed containers that are upright and secure. Ensure that persons transporting the product know what to do in the event of an accident or spillage.

SpecialProvisions