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EC number: 222-908-8 | CAS number: 3658-77-3
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- experimental dates: 15 May to 07 June 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- The study was conducted according to an internationally recognised method, and under GLP, without deviation. The substance is adequately characterised. Therefore full validation applies.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 23. Mar. 2006
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- Regulation (EC) N°440/2008, as modified by Reg.(EC) No 761/2009
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Landesamt für Umwelt, Wasserwirtschaft und Gewerbeaufsicht (inspected on 13 & 14 October 2014, 2010 / signed on 08 April 2015)
- Type of method:
- effusion method: Knudsen cell
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0.81 Pa
- Conclusions:
- Low volatility (based on volatility bands criteria for occupational exposure (Chesar / ECETOC TRA), << 500 Pa).
- Executive summary:
The vapour pressure of the test substance was measured under GLP according to OECD 104 / EU A4 guideline, effusion method with Knudsen cell (weight loss).
Determinations were conducted at 30, 45 and 60 °C, with triplicate measurements for each of the four cells.
The vapour pressure at 25°C of the test item was extrapolated from the regression as 0.81 Pa.
Reference
Parameter |
T |
Mean P |
1/T |
log VP |
Unit |
K (°C) |
Pa |
1/K |
log Pa |
Values |
303.2 (30.0) |
1.02 |
3.2982E-03 |
0.0095 |
318.2 (45.0) |
2.6 |
3.1427E-03 |
0.4064 |
|
333.2 (60.0) |
4.5 |
3.0012E-03 |
0.6484 |
A graph with log VP vs. 1/T was plotted. Since the values were correlated by a linear relation, the data could be fitted by linear regression:
Slope = -2158.0
Intercept = 7.1468
Correlation Coefficient r = -0.9938
Coefficient of Determination r2 = 0.9875
The vapour pressures at 20°C and at 25°C were calculated from the regression equation (mean value, rounded for accuracy/SD):
Vapour pressure at 20°C = 0.61 Pa
Vapour pressure at 25°C = 0.81 Pa
Description of key information
Low volatility.
Key value for chemical safety assessment
- Vapour pressure:
- 0.81 Pa
- at the temperature of:
- 25 °C
Additional information
A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. Therefore, it is considered as a key study, and the result is retained as key data.
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