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Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

The effective concentration (EC50) of sodium 2-(2-dodecyloxyethoxy) ethyl sulphate in a aquatic green algae (Pseudokirchnerella subcapitata) in a 72 hr study on the basis of growth effect was estimated to be 115.072 mg/L.Thus,considering the CLP Criteria for aquatic classification of the substance , it is concluded that sodium 2-(2-dodecyloxyethoxy) ethyl sulphate does not exhibit toxicity to algae.

Key value for chemical safety assessment

EC50 for freshwater algae:
115.072 mg/L

Additional information

Based on the various studies available with Klimish rating 2 for the target substance CAS NO 3088-31-1 and read across substances and based on the category approach of organic functional group along with similar mechanistic approach and having structural similarities defined by QSAR toolbox. The results is summarized as follows

 

Sr.No

Endpoint

Effect values

Basis for effects

Duration

Species

Remarks

1

EC50

115.072mg/l

growth rate

72 hrs

Pseudokirchnerella subcapitata

Predicted data for target chemical

2

EC50

100 mg/l

Cell changes

24 hrs

Laminaria hyperborea

Data from publication for CAS no 9004-82-4

3

EC50

117mg/l

growth inhibition

4 days

Seleriastrum Capricornutum

Data from publication for CAS no 151-21-3

4

EC50

1550mg/l

growth inhibition

6 hrs

Seleriastrum Capricornutum

Data from publication for CAS no 151-21-3

 

By applying weight of evidence approach to the studies summarized in the above table it can be observed that EC50 value is expected to be in range of100 to1550 mg/l in 6 hrs to 72 hrs study. Thus considering CLP Criteria for aquatic classification of the substance, it is concluded that Sodium 2-(2-dodecyloxyethoxy) ethyl sulphate does not exhibit toxicity to green algae (Pseudokirchnerella subcapitata, Laminaria hyperborea  and Seleriastrum Capricornutum.)