Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 221-111-2 | CAS number: 3006-86-8
Biodegradation in soil
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in soil: simulation testing
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Please refer to read-across justification attached to IUCLID Section 13.
- Reason / purpose for cross-reference:
- read-across source
- Remarks on result:
- other: to be submitted as soon as the study is finalised
- Transformation products:
- not specified
- Endpoint:
- biodegradation in soil: simulation testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2022-2023
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- This information will be submitted later based on ECHA communication/decision number CCH-D-2114476254-46-01/F.
A study with the analogue substance, TMCH, CAS 6731-36-8, according to OECD 307 is currently ongoing. Due to the COVID-19 pandemic and the shortage in 14C supply in Europe, the synthesis of a stable radiolabelled material for the test has been delayed significantly. In addition, it was quite challenging to find a CRO willing to synthesise a 14C organic peroxide and by the time a sample was available all free slots at the competent CRO were already booked ahead of time.
Due to the volatility issues with the target substance, a read-across to the structural analogue will be performed. The study will be submitted in a dossier update as soon as it is available. - Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 307 (Aerobic and Anaerobic Transformation in Soil)
- GLP compliance:
- yes
- Remarks on result:
- other: to be submitted as soon as the study is finalised
- Transformation products:
- not specified
Referenceopen allclose all
Description of key information
A study with the structural analogue is ongoing. For more details, please refer to the study record.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
