Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 220-509-3 | CAS number: 2786-76-7
Toxicological Summary
Administrative data
Workers - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Workers - Hazard via dermal route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
Workers - Hazard for the eyes
Local effects
- Hazard assessment conclusion:
- no hazard identified
Additional information - workers
Worker DNELs have not been derived for Pigment Red 170 because the substance did not cause relevant toxictiy in any test performed according to the information requirements.
- the substance did not cause lethal effects in rats after administration of a single oral dose of 15000 mg/kg, a single dermal dose of 2000 mg/kg or a single inhalation exposure to 1580 mg/cubic metre,
- the substance isnot irritating and does not have to be classified as eye or skin irritants,
- the substance caused no relevant systemic toxic effects in a subacute oral study in rats (NOAEL 1000 mg/kg/day),
- a close structural analogue of the substance caused no relevant systemic toxic effects in a subchronic inhalation study in rats (NOAEC 30 mg/m³),
- the substance caused no systemic toxic effects, no effects on fertility or development in a Reproduction / Developmental Toxicity Screening Test (OECD TG 421; NOAEL 1000 mg/kg bw/day),
- a close structural analogue of the substance caused no relevant systemic toxic effects in a two developmental toxicity studies in rats and rabbits (NOAEL 1000 mg/kg/day),
- the absence of effects in the above-mentioned toxicity endpoint tests indicates that the substance does not interact with living cells/tissues, and
- it is unlikely that the substance become systemically bioavailable due to their extremely low solubility in water and low solubility in n-octanol. The substance is not likely to be systemically available after oral, dermal or inhalation exposure.
Therefore no DNELs for systemic effects have been derived.
Pigment Red 170 does not cause irritation, corrosion or sensitization. It is considered unlikely to become bioavailable in the skin and is not classified regarding respiratory tract irritation. No substance specific effects are expected for the Pigment Red 170 after local exposure, therefore no DNELs for local effects have been derived. Apart from that, relevant occupational exposure limits for inert dusts should be applied.
General Population - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
General Population - Hazard via dermal route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
General Population - Hazard via oral route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
General Population - Hazard for the eyes
Local effects
- Hazard assessment conclusion:
- no hazard identified
Additional information - General Population
DNELs for the general population have not been derived for Pigment Red 170 because the substance did not cause relevant toxictiy in any test performed according to the information requirements.
- the substance did not cause lethal effects in rats after administration of a single oral dose of 15000 mg/kg, a single dermal dose of 2000 mg/kg or a single inhalation exposure to 1580 mg/cubic metre,
- the substance isnot irritating and does not have to be classified as eye or skin irritants,
- the substance caused no relevant systemic toxic effects in a subacute oral study in rats (NOAEL 1000 mg/kg/day),
- a close structural analogue of the substance caused no relevant systemic toxic effects in a subchronic inhalation study in rats (NOAEC 30 mg/m³),
- the substance caused no systemic toxic effects, no effects on fertility or development in a Reproduction / Developmental Toxicity Screening Test (OECD TG 421; NOAEL 1000 mg/kg bw/day),
- a close structural analogue of the substance caused no relevant systemic toxic effects in a two developmental toxicity studies in rats and rabbits (NOAEL 1000 mg/kg/day),
- the absence of effects in the above-mentioned toxicity endpoint tests indicates that the substance does not interact with living cells/tissues, and
- it is unlikely that the substance become systemically bioavailable due to their extremely low solubility in water and low solubility in n-octanol. The substance is not likely to be systemically available after oral, dermal or inhalation exposure.
Therefore, no DNELs for systemic effects have been derived.
Pigment Red 170 does not cause irritation, corrosion or sensitization. It is considered unlikely to become bioavailable in the skin and is not classified regarding respiratory tract irritation. No substance specific effects are expected for the Pigment Red 170 after local exposure, therefore no DNELs for local effects have been derived. Apart from that, relevant occupational exposure limits for inert dusts should be applied.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
