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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
Edition dated 27.07.95
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Key result
Water solubility:
3.65 g/L
Conc. based on:
test mat.
Incubation duration:
96 h
Temp.:
30 °C
pH:
4.7
Remarks on result:
other: mean value of 3 measurements
Conclusions:
The GLP study was performed according to OECD TG 105 without any deviations on the substance to be registered itself, the results were so obtained via a scientifically reasonable method. Hence, there is no doubt that the obtained results are not reliable: The water solubility was determined to be 3.65 g/L; the substance is soluble in water.
Executive summary:

The water solubility of 3-Methyl-thiazolidin-thion-2 was determined in a GLP guideline study according to OECD 105 using the flask method. According to the definition of the OECD-Guideline 105 the test item shows a water solubility of 3.65 g/L; the substance is soluble in water.

All data indicate a stability of the test item during the period of test and within the test conditions.

Due to a relative standard deviation of < 15 % the test can be stated as valid. The criteria of the OECD 105 "[...] at least the two last vessels do not differ by more than 15 % [..]" was not applied due to the fact that the first of the three vessel had a higher concentration as the second vessel. Therefore the deviation of all three vessels was taken under consideration. The determined concentrations are not recovery corrected.

Description of key information

Water solubility: 3.65 g/L (at 30°C and pH 4.7) [exp. result, OECD 105, flask method, GLP]

Key value for chemical safety assessment

Water solubility:
3.56 g/L
at the temperature of:
30 °C

Additional information

The test item was tested in a GLP study according to OECD-Guideline 105 with the "Flask Method" (without any deviations on the substance to be registered itself, the results were so obtained via a scientifically reasonable method). According to the definition of the OECD-Guideline 105 the test item shows a water solubility of 3.65 g/L; the substance is soluble in water.