Registration Dossier
Registration Dossier
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EC number: 217-440-6 | CAS number: 1852-04-6
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 5 000 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 6 000 mg/kg bw
Additional information
After oral administration of disodium sebacate to rats and rabbits, no oral toxicity was found. No dermal toxicity was also detected on rabbits after dermal administration of dodecanedioic acid. Based on a read across (category approach), no acute toxicity is expected for undecanedioic acid.
Justification for classification or non-classification
The LD50 by oral route was found higher than 5000 mg/kg bw and for dermal route higher than 6000 mg/kg bw. According to the Dangerous Substances Directive (67/548/EC) and CLP regulation (1272/2008/EC), no classification regarding the oral acute toxicity for disodium sebacate and dermal acute toxicity for dodecanedioic acid is required. The same applies for undecanedioic acid, based on a read across among category members.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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