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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The method used was recommended by the EU Directive 92/69/EEC, which was modified to take into account the tendency of the material to hydrolyze.
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
yes
Remarks:
Reduced equilibration time to avoid hydrolysis
Principles of method if other than guideline:
Distilled water and the substance were combined in each of four conical flasks. The contents were stirred at 20°C for 48 hours and 24 hours. A shorter equilibration time, that recommended by the test method was used because epoxy resin was known to hydrolyze. The excess test substance floated to the surface and onto the surface of the stirring bar leaving a clear saturated aqueous solution for analysis. A portion of the clear solution was recarefully removed from the flask and analyzed by HPLC using direct injection of the sample.
GLP compliance:
yes
Type of method:
flask method
Water solubility:
> 5.4 - < 8.4 mg/L
Temp.:
20 °C
pH:
>= 6.12 - <= 6.64
Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility of EPIKOTE(TM) 828 has been determined using the flask method. The result obtained was 6.9+/-1.5 mg/L at 20°C.
Executive summary:

A study was performed to determine the water solubility of EPIKOTE(TM) 828. The method was amongst those described in EEC Methods for the determination of physicochemical properties, Directive 92/69/EEC (OJ No. L 383A, 29.12.92), Part A, Methods A1 - A7. the physicochemical property determined in this study together with the result obtained is given below.

EEC Method Test Result

A6 Water solubility 6.9 +/- 1.5 mg/l at 20°C

Description of key information

The water solubility of substance EC number 500-033-5 was found to be 6.9 mg/L. The substance EC number 500-033-5 is slightly soluble in water.

Key value for chemical safety assessment

Water solubility:
6.9 mg/L
at the temperature of:
20 °C

Additional information