Registration Dossier
Registration Dossier
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EC number: 215-524-7 | CAS number: 1328-53-6 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 74260.
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to fish
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- LC50
- Effect concentration:
- > 100 mg/L
Additional information
For the assessment of acute toxicity of Polychloro copper phthalocyanine (CAS 1328-53-6) to fish experimental data are available.
A GLP key study conducted similar to OECD TG 203 was performed by Colour-Chem limited (2000). Cyprinus carpio was used as a test organism. In this limit test no mortality of fish was observed at the end of the test, therefore the 96-h LC50 was determined to be higher than 100 mg/L (nominal). In this study Tween-80 was used as a vehicle. The concentration of the vehicle was 1 g/L.
There are further experimental data which support the key result. Additionally, two non-GLP tests conducted according to EPA-660/3-75-009 were performed by Sun Chemical Corporation (1978). In a test conducted with Lepomis macrochirus the 96-h LC50 was determined to be 752.4 mg/l (nominal, rep. no.: 11506-62-01). Whereas in a second test conducted with Oncorhynchus mykiss as a test organism the 96-h LC50 was determined to be 355.6 mg/L (nominal, rep. no.: 11506-03-02). No vehicle was used in both studies.
The test concentrations were not analytically verified in all studies.
Overall, based on the available experimental data for the test substance, it is considered that the CAS 1328-53-6 is with high probability acutely not harmful to fish.
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