Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 212-786-4 | CAS number: 869-24-9
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 150 mg/L
Additional information
The acute toxicity of P5524 (which contains 99.9% DEC) to rainbow trout (Oncorhynchus mykiss) was determined in a static GLP compliant test according to EU method C.1 and OECD 203 (Bell 1996). The test was started with a Control (0), 10, 22, 46, 100, and 220 mg test item/L. Dose verification at hour 0 and hour 72 confirmed that the test solutions were correctly dosed (recoveries of the biologically relevant concentrations in general within 80 - 120%. For each test concentration and the control, 1 replicate with 7 fish (mean total length 5.5 cm, average weight 2.16 g/fish) each were set up in 18 L test solution (glass vessels). The test was performed in a 16:8 h light dark cycle. The concentrations were reported as nominal concentrations. After 96 hours of exposure, 0, 0, 0, 0, 0, 0, and 100 % of the daphnids were immobilized at Control, 10, 22, 46, 100, and 220 mg test item/L. The corresponding 96 h LC50 value is 150 mg test item/L.
This study was performed according to international guidelines and under GLP and fulfilled the validity criteria. Correct dosing was verified. Therefore, this study was considered to be Klimisch 1 study.
The obtained results are considered as relevant for the risk assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
