Registration Dossier
Registration Dossier
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EC number: 211-673-7 | CAS number: 683-60-3
Guidance on Safe Use
Guidance on Safe Use
Administrative data
First-aid measures
Description of first aid measures
Pay attention to self-protection.
Remove victims from hazardous area. Immediately remove soiled or soaked clothing and remove it to a safe distance. Keep victim warm, in a stabilized position and covered.
Do not leave victims unattended.
If the casualty is unconscious: Place the victim in the recovery position.
Inhalation
Potential for exposure by inhalation if aerosols or mists are generated.
Move victims into fresh air.
With labored breathing: Provide with oxygen. Consult a doctor.
If the casualty is not breathing: Perform mouth-to-mouth resuscitation, notify emergency physician immediately.
Skin contact
Wash off affected area immediately with plenty of water for at least 15 minutes.
If symptoms persist, consult a physician for treatment.
Eye contact
With eye held open, thoroughly rinse immediately with plenty of water for at least 10 minutes.
Consult an ophthalmologist immediately if the symptoms persist.
When dealing with caustic substances, notify emergency physician immediately (key words: burns in eye).
Ingestion
Rinse mouth.
Immediately give large quantities of water to drink.
Obtain medical attention.
When dealing with caustic substances, notify emergency physician immediately.
Most important symptoms and effects, both acute and delayed
Symptoms
Irritation of skin and mucous membranes
Causes burns.
daze,
Headache, vertigo, somnolence (sleepiness), nausea.
Health injuries may be delayed.
Hazards
Strongly irritating to corrosive.Harmful in contact with skin and if swallowed.
Vapours may cause drowsiness and dizziness.
Indication of any immediate medical attention and special treatment needed
The initial focus is only on the local action, characterized by quickly progressing deep tissue damage.
In the eye, caustic/ irritating and harmful liquids cause, depending on the intensity of exposure, various levels of irritation, destruction, and ablation of the epithelium of the conjunctiva and cornea, corneal clouding, edema and ulcerations.
Danger! Possible loss of eyesight!
Superficial irritations and damage up to ulcerations and scarring develop on the skin.
After accidental absorption in the body, the pathology and clinical findings are dependent on the kinetics of the substance (quantity of absorbed substance, the absorption time, and the effectiveness of early elimination measures (first aid)/ excretion - metabolism).
A specific action of the substance is unknown.
In case of substances with high water solubility, irritations up to formation of necrosis in the upper respiratory tract may result after inhalation of caustic/ irritating aerosols and mists.
The initial focus is on the local action: signs of irritation of the respiratory tract such as coughing, burning behind the sternum, tears, burning in the eyes or nose.
There is a risk of pulmonary edema!
Pay attention to self-protection.
Remove victims from hazardous area. Immediately remove soiled or soaked clothing and remove it to a safe distance. Keep victim warm, in a stabilized position and covered.
Do not leave victims unattended.
If the casualty is unconscious: Place the victim in the recovery position.
Inhalation
Potential for exposure by inhalation if aerosols or mists are generated.
Move victims into fresh air.
With labored breathing: Provide with oxygen. Consult a doctor.
If the casualty is not breathing: Perform mouth-to-mouth resuscitation, notify emergency physician immediately.
Skin contact
Wash off affected area immediately with plenty of water for at least 15 minutes.
If symptoms persist, consult a physician for treatment.
Eye contact
With eye held open, thoroughly rinse immediately with plenty of water for at least 10 minutes.
Consult an ophthalmologist immediately if the symptoms persist.
When dealing with caustic substances, notify emergency physician immediately (key words: burns in eye).
Ingestion
Rinse mouth.
Immediately give large quantities of water to drink.
Obtain medical attention.
When dealing with caustic substances, notify emergency physician immediately.
Most important symptoms and effects, both acute and delayed
Symptoms
Irritation of skin and mucous membranes
Causes burns.
daze,
Headache, vertigo, somnolence (sleepiness), nausea.
Health injuries may be delayed.
Hazards
Strongly irritating to corrosive.Harmful in contact with skin and if swallowed.
Vapours may cause drowsiness and dizziness.
Indication of any immediate medical attention and special treatment needed
The initial focus is only on the local action, characterized by quickly progressing deep tissue damage.
In the eye, caustic/ irritating and harmful liquids cause, depending on the intensity of exposure, various levels of irritation, destruction, and ablation of the epithelium of the conjunctiva and cornea, corneal clouding, edema and ulcerations.
Danger! Possible loss of eyesight!
Superficial irritations and damage up to ulcerations and scarring develop on the skin.
After accidental absorption in the body, the pathology and clinical findings are dependent on the kinetics of the substance (quantity of absorbed substance, the absorption time, and the effectiveness of early elimination measures (first aid)/ excretion - metabolism).
A specific action of the substance is unknown.
In case of substances with high water solubility, irritations up to formation of necrosis in the upper respiratory tract may result after inhalation of caustic/ irritating aerosols and mists.
The initial focus is on the local action: signs of irritation of the respiratory tract such as coughing, burning behind the sternum, tears, burning in the eyes or nose.
There is a risk of pulmonary edema!
Fire-fighting measures
Extinguishing media
Suitable extinguishing media:
dry sand
dry powder
Alcohol-resistant foam
Unsuitable extinguishing media:
water
CO2
water spray
high volume water jet
Halons
Special hazards arising from the substance or mixture
Hazard-determining flue gases might develop in case of fire:
Carbon monoxide
Carbon dioxide (CO2)
Forms explosive mixtures with air.
With large-scale fire, violent decomposition or even explosion is possible.
Advice for firefighters
Water for fire fighting must not be introduced in the sewer system, subsoil, or surface waters. Assure that there are sufficient fire water retaining facilities Contaminated fire fighting water must be disposed of in conformity with the regulations of the local authorities.
Fire residues should be disposed of in accordance with the regulations.
In case of fire: full protective suit and wear a self contained respiratory apparatus
Suitable extinguishing media:
dry sand
dry powder
Alcohol-resistant foam
Unsuitable extinguishing media:
water
CO2
water spray
high volume water jet
Halons
Special hazards arising from the substance or mixture
Hazard-determining flue gases might develop in case of fire:
Carbon monoxide
Carbon dioxide (CO2)
Forms explosive mixtures with air.
With large-scale fire, violent decomposition or even explosion is possible.
Advice for firefighters
Water for fire fighting must not be introduced in the sewer system, subsoil, or surface waters. Assure that there are sufficient fire water retaining facilities Contaminated fire fighting water must be disposed of in conformity with the regulations of the local authorities.
Fire residues should be disposed of in accordance with the regulations.
In case of fire: full protective suit and wear a self contained respiratory apparatus
Accidental release measures
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.
Keep away from sources of ignition - No smoking.
Keep unauthorized persons away.
Environmental precautions
Do not allow entrance in sewage water, drainage systems, stretches of water, soil.
Observe regulations on prevention of water pollution (check, dam up, cover up).
Methods and material for containment and cleaning up
Use mechanical handling equipment.
Fill into marked, sealable containers.
Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local / national regulations.
Suitable absorbents:
dry sand
ground limestone
Absorbents not to be used:
sawdust
Reference to other sections
Wear personal protective equipment; see section 8.
Use personal protective equipment.
Keep away from sources of ignition - No smoking.
Keep unauthorized persons away.
Environmental precautions
Do not allow entrance in sewage water, drainage systems, stretches of water, soil.
Observe regulations on prevention of water pollution (check, dam up, cover up).
Methods and material for containment and cleaning up
Use mechanical handling equipment.
Fill into marked, sealable containers.
Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local / national regulations.
Suitable absorbents:
dry sand
ground limestone
Absorbents not to be used:
sawdust
Reference to other sections
Wear personal protective equipment; see section 8.
Handling and storage
Precautions for safe handling
Use permissible in closed systems only. Handle and transfer product in closed systems only (gas displacement device).
Ensure that apparatus and pipelines are free from leaks. Do not ventilate into the open.
Suitable loading and unloading device required.
Conditions for safe storage, including any incompatibilities
Advice on protection against fire and explosion
Take precautionary measures against static discharges.
Keep away from sources of ignition - No smoking.
No sparking tools should be used.
In use, may form flammable/explosive vapour-air mixture.
Storage
Store in the original receptacle, keeping this tightly sealed, under cool and dry conditions.
Protect from warming.
Avoid humidity and water.
Storage under inert gas (nitrogen) recommended.
Suitable materials stainless steel
Unsuitable materials light metals and their alloys
Further information
In order to ensure due transportation, make certain that stacks are of the correct height, containers are securely fastened so as not to fall off, and labelled according to the regulations.
German storage class
3 - Flammable Liquids
Use permissible in closed systems only. Handle and transfer product in closed systems only (gas displacement device).
Ensure that apparatus and pipelines are free from leaks. Do not ventilate into the open.
Suitable loading and unloading device required.
Conditions for safe storage, including any incompatibilities
Advice on protection against fire and explosion
Take precautionary measures against static discharges.
Keep away from sources of ignition - No smoking.
No sparking tools should be used.
In use, may form flammable/explosive vapour-air mixture.
Storage
Store in the original receptacle, keeping this tightly sealed, under cool and dry conditions.
Protect from warming.
Avoid humidity and water.
Storage under inert gas (nitrogen) recommended.
Suitable materials stainless steel
Unsuitable materials light metals and their alloys
Further information
In order to ensure due transportation, make certain that stacks are of the correct height, containers are securely fastened so as not to fall off, and labelled according to the regulations.
German storage class
3 - Flammable Liquids
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 2924
Shippingopen allclose all
SpecialProvisionsopen allclose all
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- 2924
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- 2924
Shipping information
- Proper shipping name and description:
- FLAMMABLE LIQUID, CORROSIVE, N.O.S. (Sodium-propan-2-olate, tetrahydrofuran)
- Chemical name:
- Sodium-propan-2-olate, tetrahydrofuran
- Labels:
- 3, 8FC
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 2924
Shipping information
- Proper shipping name and description:
- Flammable liquid, corrosive, n.o.s. (Sodium-propan-2-olate, tetrahydrofuran)
- Chemical name:
- Sodium-propan-2-olate, tetrahydrofuran
- Labels:
- 3, 8
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Exposure controls
Engineering measures
Refill and handle product only in closed system.
Leak detection recommended
Wastewater can be added to a biological wastewater treatment plant.
Remove exhaust gases through a washer or through combustion.
Minimization of emissions by means of suitable technical measures such as flanges and valves with low leakage rates, recirculation of vapours.
All precautionary measures indicated have to be observed.
Exposure controls
The substance must be handled under strictly controlled conditions in accordance with Article 17/18 of the REACH regulation.
Personal protective equipment
Respiratory protection
Accidental release measures
use respiratory equipment with suitable filter (filter type P3) or wear a self contained respiratory apparatus
Note time limit for wearing respiratory protective equipment.
Hand protection
Accidental release measures
Glove material: Nitrile/Chloroprene, for example:, Nitopren 717
Material thickness: 0,65 mm
Break through time: < 30 min
Method: DIN EN 374
Selection of protective gloves to meet the requirements of specific workplaces.
Suitability for specific workplaces should be clarified with protective glove manufacturers.
Remember that the useful time per day of a chemical protection glove may be much shorter than the permeation time determined according to EN 374 due to the many different influential factors involved (e.g. temperature).
Eye protection
close-fitting protective goggles (e.g. closed goggles)
Skin and body protection
suitable protective clothing in case of leakage
Personal protection through wearing a tightly closed chemical protection suit and a self-contained breathing apparatus.
suitable protective clothing - Use disposable clothing if appropriate.
Hygiene measures
Remove and wash contaminated clothing before re-use.
Do not eat, drink, smoke, or sniff while at work. Wash your hands and/or face before breaks and before termination of work.
Preventive skin protection is recommended.
Use barrier cream regularly.
Protective measures
All precautionary measures indicated have to be observed.
Risk assessment and risk monitoring of all work places required.
Health, Safety and Emergency Management System recommended.
Written approval necessary in case of non-routine jobs, e.g. maintenance activities.
Regular safety training is a must.
The personal protective equipment used must meet the requirements of Regulation (EU) 2016/425 and amendments (CE certification).
It should be defined in the work place in the form of a risk analysis according to Regulation (EU) 2016/425 and amendments.
Environmental exposure controls
Emissions from venting and processing equipment should be checked in order to ensure that the requirements of the Environmental Protection Law are satisfied.
In some cases, exhaust air scrubbers, filters or technical changes to the processing plant will be required in order to decrease emissions to acceptable values.
Engineering measures
Refill and handle product only in closed system.
Leak detection recommended
Wastewater can be added to a biological wastewater treatment plant.
Remove exhaust gases through a washer or through combustion.
Minimization of emissions by means of suitable technical measures such as flanges and valves with low leakage rates, recirculation of vapours.
All precautionary measures indicated have to be observed.
Exposure controls
The substance must be handled under strictly controlled conditions in accordance with Article 17/18 of the REACH regulation.
Personal protective equipment
Respiratory protection
Accidental release measures
use respiratory equipment with suitable filter (filter type P3) or wear a self contained respiratory apparatus
Note time limit for wearing respiratory protective equipment.
Hand protection
Accidental release measures
Glove material: Nitrile/Chloroprene, for example:, Nitopren 717
Material thickness: 0,65 mm
Break through time: < 30 min
Method: DIN EN 374
Selection of protective gloves to meet the requirements of specific workplaces.
Suitability for specific workplaces should be clarified with protective glove manufacturers.
Remember that the useful time per day of a chemical protection glove may be much shorter than the permeation time determined according to EN 374 due to the many different influential factors involved (e.g. temperature).
Eye protection
close-fitting protective goggles (e.g. closed goggles)
Skin and body protection
suitable protective clothing in case of leakage
Personal protection through wearing a tightly closed chemical protection suit and a self-contained breathing apparatus.
suitable protective clothing - Use disposable clothing if appropriate.
Hygiene measures
Remove and wash contaminated clothing before re-use.
Do not eat, drink, smoke, or sniff while at work. Wash your hands and/or face before breaks and before termination of work.
Preventive skin protection is recommended.
Use barrier cream regularly.
Protective measures
All precautionary measures indicated have to be observed.
Risk assessment and risk monitoring of all work places required.
Health, Safety and Emergency Management System recommended.
Written approval necessary in case of non-routine jobs, e.g. maintenance activities.
Regular safety training is a must.
The personal protective equipment used must meet the requirements of Regulation (EU) 2016/425 and amendments (CE certification).
It should be defined in the work place in the form of a risk analysis according to Regulation (EU) 2016/425 and amendments.
Environmental exposure controls
Emissions from venting and processing equipment should be checked in order to ensure that the requirements of the Environmental Protection Law are satisfied.
In some cases, exhaust air scrubbers, filters or technical changes to the processing plant will be required in order to decrease emissions to acceptable values.
Stability and reactivity
Reactivity
No further information available
Chemical stability
No further information available
Possibility of hazardous reactions
Exothermic reaction with:
water
oxidizing agents
Acids
Chlorocarbons
Potential spontaneous combustion due to air moisture
Formation of peroxides may occur (in the presence of light and atmospheric oxygen).
Conditions to avoid
atmospheric humidity
Keep away from heat and sources of ignition.
Avoid contact with air/oxygen (formation of peroxides)
Incompatible materials
water, Oxidizing agents, Acids, halogens, Halogenated compounds, danger of spontaneous ignition., Vigorous reaction on contact with water and air humidity.
Hazardous decomposition products
Decomposition products from hydrolysis in water
sodium hydroxide
2-propanol
Decomposition products in combustion and thermal decomposition
Carbon dioxide (CO2)
Carbon monoxide
sodium hydroxide
No further information available
Chemical stability
No further information available
Possibility of hazardous reactions
Exothermic reaction with:
water
oxidizing agents
Acids
Chlorocarbons
Potential spontaneous combustion due to air moisture
Formation of peroxides may occur (in the presence of light and atmospheric oxygen).
Conditions to avoid
atmospheric humidity
Keep away from heat and sources of ignition.
Avoid contact with air/oxygen (formation of peroxides)
Incompatible materials
water, Oxidizing agents, Acids, halogens, Halogenated compounds, danger of spontaneous ignition., Vigorous reaction on contact with water and air humidity.
Hazardous decomposition products
Decomposition products from hydrolysis in water
sodium hydroxide
2-propanol
Decomposition products in combustion and thermal decomposition
Carbon dioxide (CO2)
Carbon monoxide
sodium hydroxide
Disposal considerations
Waste treatment methods
Product
Strictly controlled conditions during disposal or treatment to air, wastewater and waste.
Wastewater can be added to a biological wastewater treatment plant.
Bring wastewater containing AOX for professional disposal.
Disposal according to local authority regulations.
Uncleaned packaging
Do not reuse empty containers and dispose of in accordance with the regulations issued by the appropriate local authorities.
Waste Key Number
The waste key number must be determined as per the European Waste Types List (decision on EU Waste Types List 2000/532/EC) in cooperation with the disposal firm / producing firm / official authority.
Product
Strictly controlled conditions during disposal or treatment to air, wastewater and waste.
Wastewater can be added to a biological wastewater treatment plant.
Bring wastewater containing AOX for professional disposal.
Disposal according to local authority regulations.
Uncleaned packaging
Do not reuse empty containers and dispose of in accordance with the regulations issued by the appropriate local authorities.
Waste Key Number
The waste key number must be determined as per the European Waste Types List (decision on EU Waste Types List 2000/532/EC) in cooperation with the disposal firm / producing firm / official authority.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
