Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 208-589-8 | CAS number: 534-15-6
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Biodegradability of 1,1-dimethoxyethane was predicted with TOPKAT and BIOWIN. TOPKAT predicts biodegradability based on training data assessed by the MITI 1 test. Poor accuracy in the prediction (all false-postitives (degradable)) of the four most similar structures in the training set and also poor concordance between their experimental results (not biodegradable) and the prediction for the query structure suggest no confidence in the TOPKAT prediction. BIOWIN predicted 1,1-dimethoxyethane not to be readily biodegradable and there is confidence in the prediction. The ultimate and primary biodegradation time frame (models Biowin 3 and 4) was predicted to be weeks and days to weeks, respectively.
Taking into account that similar structured acetal dimethoxymethane is not considered to be readily biodegradable (see, ECHA registration dossiers) there is an argument for a weight of evidence that 1,1-dimethoxyethane is not readily biodegradable.
Prediction results of biodegradability of 1,1-dimethoxyethane
Model |
Biodegradability |
Reliability |
TOPKAT |
Degradable |
Not reliable |
BIOWIN |
Not readily degradable |
reliable |
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
