Quinazolin-4(1H)-one

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 2018-01-29 to 2018-03-30

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

GLP compliance:

yes

Type of method:

effusion method: Knudsen cell

Specific details on test material used for the study:

Batch No.: 20170707
Purity: 99.13%

Key result

Test no.:

#1

Temp.:

114 °C

Vapour pressure:

9.792 Pa

Key result

Test no.:

#2

Temp.:

116 °C

Vapour pressure:

10.755 Pa

Key result

Test no.:

#3

Temp.:

118 °C

Vapour pressure:

12.056 Pa

Key result

Test no.:

#4

Temp.:

120 °C

Vapour pressure:

13.28 Pa

Key result

Temp.:

20 °C

Vapour pressure:

0.015 Pa

Remarks on result:

other: Extrapolated to 20°C

Conclusions:

The vapor pressure of test item extrapolated to 20°C is 0.014955 Pa.

Executive summary:

The vapor pressure of the test substance by Knudsen effusion method was measured using a Surface Measurement System VPA-1, vapor pressure analyzer based on the methodology referenced in OPPTS 830.7950 and OECD 104. The Knudsen effusion method is a dynamic

gravimetric technique based on the rate of escape of vapor molecules through an orifice of known dimension in a Knudsen cell into a vacuum at a known temperature. The rate of mass loss through the orifice per unit of time was measured and used to calculate the vapor pressure. Calculations were performed using VPA Analysis: DVS Std v 7.1.0 (includes VPA analysis Software v0.6).

The vapor pressure of test item extrapolated to 20°C is 0.014955 Pa.

Description of key information

The vapor pressure of test item extrapolated to 20°C is 0.014955 Pa.

Key value for chemical safety assessment

Vapour pressure:

0.015 Pa

at the temperature of:

20 °C