Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
09 March 2016 to 20 July 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report date:
2016

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
N-2-hydroxyethylacetamide
EC Number:
205-530-8
EC Name:
N-2-hydroxyethylacetamide
Cas Number:
142-26-7
Molecular formula:
C4H9NO2
IUPAC Name:
N-2-hydroxyethylacetamide
Test material form:
liquid

Results and discussion

Water solubility
Key result
Temp.:
20 °C
pH:
5.6 - 7.3
Remarks on result:
completely miscible

Any other information on results incl. tables

Sample

Concentration (% w/w)

Observations

Solution pH

1

5.07

Single phase, clear, colourless solution.

5.6

2

50.0

Single phase, pale straw-coloured solution.

6.3

3

94.8

Single phase, straw-coloured solution

7.3

Applicant's summary and conclusion

Conclusions:
The test item has been determined to be miscible with water in all proportions at 20.0 ± 0.5 °C.
Executive summary:

The test substance was miscible with water in all proportions at 20.0 ± 0.5 °C, by visual assessment using a flask method at 5, 50 and 95% w/w, designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.