Registration Dossier
Registration Dossier
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EC number: 203-620-1 | CAS number: 108-83-8
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.03 mg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.3 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.003 mg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 2.55 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.46 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.046 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.075 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
This aliphatic ketone has a log Kow of 3.71 and a predicted BCF of 130 L/kg, is not expected to bioaccumulate and is readily biodegradable. Diisobutyl ketone s is expected to be effectively removed during activated sludge sewage treatment and is not expected to occupy the water, sediment or soil compartments. The risk assessment shows that the PEC/PNEC ratio is clearly <1, indicating no need for further information or testing is needed for the aquatic environment. According to REACH Annex IX requirements, long-term toxicity testing shall only be considered when the chemical safety assessment indicates the need for further investigation. Therefore, long-term testing in aquatic species (fish and daphnid) can be waived for diisobutyl ketone. Due to limited direct or indirect exposure to the soil compartment, terrestrial toxicity testing is also waived.
Conclusion on classification
Diisobutyl ketone is readily biodegradable with acute aquatic toxicity values falling between 10 and 100 mg/L. According to Annex VI of Directive 67/548/EEC (5.2.1.2) there is no environmental classification requirement.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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