Registration Dossier
Registration Dossier
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EC number: 203-577-9 | CAS number: 108-39-4
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to soil microorganisms
- Data waiving:
- exposure considerations
- Justification for data waiving:
- the study does not need to be conducted because direct and indirect exposure of the soil compartment is unlikely
- Justification for type of information:
- No valid experimental study on toxicity to terrestrial microorganisms is available. In accordance with column 2 of REACH Annex X of Regulation EC 1907/2006performing of a study is not necessary, as the risk assessment does not indicate the need to investigate further the effects of the substance on terrestrial organisms. According to Guidance Document R.7c (v3.0; 2017) it is stated, that for readily biodegradable substances which are not directly applied to soil it is generally assumed that the substance will not enter the terrestrial environment and as such there is no need for testing of soil organisms is required. Additionally, the substance cannot be regarded as adsorptive with a log Kow of 1.96 (logKow < 3) and logKoc of 1.54 (log Koc < 5) and is not toxic to aquatic organisms. Hence, the risk to soil organisms exposed to the substance is acceptable based on the PNECsoil calculated using the Equilibrium Partitioning Method and does not need to be refined using long-term tests.
Reference
Description of key information
No valid experimental study on toxicity to terrestrial microorganisms is available. In accordance with column 2 of REACH Annex X of Regulation EC 1907/2006performing of a study is not necessary, as the risk assessment does not indicate the need to investigate further the effects of the substance on terrestrial organisms. According to Guidance Document R.7c (v3.0; 2017) it is stated, that for readily biodegradable substances which are not directly applied to soil it is generally assumed that the substance will not enter the terrestrial environment and as such there is no need for testing of soil organisms is required. Additionally, the substance cannot be regarded as adsorptive with a log Kow of 1.96 (logKow < 3) and logKoc of 1.54 (log Koc < 5) and is not toxic to aquatic organisms. Hence, the risk to soil organisms exposed to the substance is acceptable based on the PNECsoil calculated using the Equilibrium Partitioning Method.
Key value for chemical safety assessment
Additional information
Schroth and Hildebrand found in a non-guideline study, that at extremely high concentrations of 1.5 % v/v the cresols are remedies against 2 plant diseases (Agrobacterium tumefaciens and Pseudomonas savastanoi) in tomato (Lycopersicum esculentum) (Schroth and Hildebrand 1968). This information is, however, unsuitable for assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
