Registration Dossier
Registration Dossier
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EC number: 203-499-5 | CAS number: 107-52-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Toxicity to algae: 72 hr EC50 >0.0022 mg/l and NOEC ≥0.0022 mg/l (measured) (highest concentration tested) (OECD 201), read-across from an analogous/structurally related substance, decamethyltetrasiloxane (L4, CAS 141-62-8).
Key value for chemical safety assessment
Additional information
There are no reliable algae toxicity data available for tetradecamethylhexasiloxane (L6, CAS 107-52-8), therefore good quality data for an appropriate structural analogue, decamethyltetrasiloxane (L4, CAS 141-62-8), have been read across.
A 96-h E(L)C50 value of >0.0022 mg/l and NOEC of ≥0.0022 mg/l (measured) (highest concentration tested) have been determined for the effects of decamethyltetrasiloxane (L4, CAS 141-62-8) on growth rate of Pseudokirchneriella subcapitata. In view of the test media preparation method/exposure regime it is likely that the test organisms were exposed predominantly to the tested substance.
Refer to IUCLID Section 6 endpoint summary (CSR Section 7.0) for further information on the approach to chemical safety assessment for this registration substance, and justification for read-across used.
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