4,4'-oxydianiline

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

29 March 2010 - 2 April 2010

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7840 (Water Solubility)

Principles of method if other than guideline:

Not applicable

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Specific details on test material used for the study:

4,4'-oxydianiline
4,4'-diaminodiphenyl ether
CAS 101-80-4

Key result

Water solubility:

0.048 g/L

Temp.:

20 °C

pH:

>= 6.49 - <= 6.71

Remarks on result:

other: determined to be 0.048 ± 0.004 g/L (95 % confidence interval) at 20 °C ± 1 °C using the shake-flask method

Details on results:

Calibration

The calibration curves were prepared on each analytical occasion. Concentrations of the calibration samples were 0.02, 0.05, 0.2, 0.5, 2, 5 and 10 test item ug /ml.
The 4,4-Diaminodiphenylether concentrations were calculated with the help of the calibration equations given in Table 2 (see below)

 Table 2. Regression data

Analytical occasion	Constant	X Coefficient	R. Squared
31 March 2010	-218	128898	1.000
1April 2010	-574	131257	1.000
2 April 2010	-622	128645	1.000

 

Measured concentrations of the test substance are summarised in Table 3. The repeatability of the determination was <15 %, and thus within the range required by the guidelines.

 

Measured concentration after 24 hours (jig/ml)	Measured concentration after 48 hours (jig/ml)	Measured concentration after 72 hours (jig/ml)
45.1	49.7	42.7
52.4	45.4	47.0
51.0	44.1	50.2
Mean: 49.5	Mean: 46.4	Mean: 46.6
Table 4. Measured pH values
Measured pH values after 24 hours	Measured pH values after 48 hours	Measured pH values after 72 hours
6.51	6.62	6.65
6.45	6.50	6.57
6.49	6.57	6.71

Conclusions:

The water solubility of 4,4-Diaminodiphenylether was determined to be 0.048 ± 0.004 g/L (95 % confidence interval) at 20 °C ± 1 °C using the shake-flask method. According to this result, the test item is considered slightly soluble (0.1-100 mg/L)

Executive summary:

The water solubility of 4,4-Diaminodiphenylether was determined to be 0.048 ± 0.004 g/L (95 % confidence interval) at 20 °C ± 1 °C using the shake-flask method.

Description of key information

The water solubility of the test item was assessed using the shake-flask method.

The water solubility of 4,4-Diaminodiphenylether was determined to be 0.048 ± 0.004 g/L (95% confidence interval) at 20 °C ± 1 °C.

Key value for chemical safety assessment

Water solubility:

0.048 g/L

at the temperature of:

20 °C