Registration Dossier
Registration Dossier
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EC number: 202-803-3 | CAS number: 99-94-5
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2003
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 211 (Daphnia magna Reproduction Test)
- Deviations:
- not specified
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Details on sampling:
- The test concentrations were measured for renewal and old test solution at the start of the test and 1, 3, 5, 7, 9, 15 and 17-day.
- Vehicle:
- no
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Daphnia magna
- Strain/clone: no data
- Justification for species other than prescribed by test guideline:
- Source: National Institute for Environmental Studies (Japan)
- Age of parental stock (mean and range, SD): < 24h
- Feeding during test
- Food type: Chlorella vulgaris,
- Amount: 0.1 - 0.2 mg
- Frequency:
ACCLIMATION
- Acclimation period: 21 - 4 weeks
- Acclimation conditions (same as test or not):
- Type and amount of food:
- Feeding frequency:
- Health during acclimation (any mortality observed):
QUARANTINE (wild caught)
- Duration:
- Health/mortality:
METHOD FOR PREPARATION AND COLLECTION OF EARLY INSTARS OR OTHER LIFE STAGES: - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 21 d
- Hardness:
- 26.2 mg/L as CaCO3
- Test temperature:
- 20 +/- 1°C
- pH:
- 6.73 to 7.75
- Nominal and measured concentrations:
- Nominal Concentrations: control, 0.10, 0.32, 1.00, 3.20 and 10.00 mg/L
Measured Concentrations: 17d; 0.101, 0.325, 10.19, 3.256 and 10.215, mg/L - Reference substance (positive control):
- no
- Key result
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 3.2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The chronic toxicity to Daphnia study determined the NOEC 3.2 mg/L
Reference
Description of key information
The chronic toxicity to Daphnia study determined the NOEC 3.2 mg/L
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 3.2 mg/L
Additional information
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