Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-625-6 | CAS number: 97-99-4
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2004-11-25 to 2005-06-26
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- gas chromatography
- Key result
- Type:
- Pow
- Partition coefficient:
- 0.722
- Temp.:
- 24.7 °C
- pH:
- ca. 6.7 - ca. 6.8
- Key result
- Type:
- log Pow
- Partition coefficient:
- -0.14
- Temp.:
- 24.7 °C
- pH:
- ca. 6.7 - ca. 6.8
- Details on results:
- See Table 2
- Conclusions:
- A log Kow of -0.14 at 24.7°C and pH 6.7 - 6.8 was determined for the substance in accordance with OECD 107 and in compliance with GLP. The result is considered reliable.
Reference
Table 2 : Measurement results of partition coefficient (Pow)
| Pow=Co/Cw | log Pow | |||||||||
| MeasuredValue | Mean | TotalMean | Standarddeviation | Measuredvalue | Mean | Totalmean | Standarddeviation | Maximumdifferance | ||
| Measurement condition-1 | a | 0.653 | 0.663 | 0.722 | 0.0471 | -0.19 | -0.18 | -0.14 | 0.0289 | 0.07 |
| b | 0.674 | -0.17 | ||||||||
| Measurement condition-2 | a | 0.737 | 0.743 | -0.13 | -0.13 | |||||
| b | 0.749 | -0.13 | ||||||||
| Measurement condition-3 | a | 0.762 | 0.761 | -0.12 | -0.12 | |||||
| b | 0.759 | -0.12 | ||||||||
Description of key information
Partition coefficient [tetrahydrofurfuryl alcohol]: -0.14 at 24.7°C and pH 6.7 - 6.8 (OECD 107)
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -0.14
- at the temperature of:
- 24.7 °C
Additional information
A measured log Kow of -0.14 at 24.7°C and pH 6.7 - 6.8 was determined for the substance in accordance with OECD 107 and in compliance with GLP. The result is considered to be reliable and selected as key study. In a secondary source to which reliability could not be assigned, a limit log Kow of <3 was reported for the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
