Registration Dossier
Registration Dossier
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EC number: 202-510-0 | CAS number: 96-49-1
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 29/11/2009 - 06/12/2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- photometric method
- Key result
- Type:
- log Pow
- Partition coefficient:
- ca. 0.11
- Temp.:
- 20 °C
- pH:
- > 5.33 - < 5.79
- Details on results:
- Vessel 1 (1:1): log Pow = 0.13
Vessel 2 (1:1): log Pow = 0.10
Vessel 3 (2:1): log Pow = -0.19
Vessel 4 (2:1): log Pow = -0.19
Vessel 5 (1:2): log Pow = 0.10
Vessel 6 (1:2): log Pow = 0.09 - Conclusions:
- The log Pow of ethylene carbonate was concluded to be 0.11 following a GLP study conducted in accordance with EU method A.8, using the shake flask method.
Reference
Due to interference, erroneous results were obtained from analysis of concentration from 2:1 octanol/water ratio. As a results log Pow was calculated using concentrations from the 1:1 and 1:2 ratios.
Description of key information
The mean log Pow of ethylene carbonate was calculated to be 0.11 following a GLP study conducted in accordance with EU test method A.8, using the shake flask method (Baker, 2010).
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 0.11
- at the temperature of:
- 20 °C
Additional information
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