Registration Dossier
Registration Dossier
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EC number: 202-269-1 | CAS number: 93-70-9
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2009-05-04
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: According to the OECD Guideline for the testing of chemicals 107.
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- no
- Principles of method if other than guideline:
- not applicable
- GLP compliance:
- no
- Remarks:
- According to ECHA Guidance (phys.chem. Studies), GLP compliance is not necessary.
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 2'-chloroacetoacetanilide
- EC Number:
- 202-269-1
- EC Name:
- 2'-chloroacetoacetanilide
- Cas Number:
- 93-70-9
- Molecular formula:
- C10H10ClNO2
- IUPAC Name:
- 2'-chloroacetoacetanilide
- Details on test material:
- Appearance: white powder
Constituent 1
Study design
- Analytical method:
- other: UV/VIS spectroscopy
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 1.32
- Temp.:
- 23 °C
- Remarks on result:
- other: Mean value
- Details on results:
- Mean LogPow = 1,32
Any other information on results incl. tables
Result:
Determination No. Ratio water : n-octanol Log Pow
A1 2:1 1,33
A2 2:1 1,33
B1 1:1 1,32
B2 1:1 1,32
C1 1:2 1,33
C2 1:2 1,32
Mean ----- 1,32
Applicant's summary and conclusion
- Conclusions:
- The partition coefficient (logPow) of substance Acetoacet-o-chloroanilide was determined according to the OECD Guideline 107,
LogPow = 1,32 (mean). - Executive summary:
The study was performed in year 2009 according to the OECD Guideline for the testing of chemicals 107.
log Pow of Acetoacet-o-chloroanilide = 1,32 (mean value)
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